Evidence map›Paper›PMID 38752873›Full record

Trial reportAging2024

Senolytic effects of exercise in human muscles require acute inflammation.

Wei-Horng Jean, Yin-Chou Lin, Pei-Yao Ang, Kazushige Goto, Chao-An Lin, Luthfia Dewi, Yu-Chieh Liao, Chih-Yang Huang, Chia-Hua Kuo

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wei-Horng JeanDepartment of Anesthesiology, Far East Memorial Hospital, New Taipei City 220, Taiwan.
Yin-Chou LinDepartment of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Taoyuan 33378, Taiwan.
Pei-Yao AngLaboratory of Exercise Biochemistry, University of Taipei, New Taipei City 11153, Taiwan.
Kazushige GotoFaculty of Sport and Health Science, Ritsumeikan University, Kusatsu 525-8577, Japan.
Chao-An LinFaculty of Sport and Health Science, Ritsumeikan University, Kusatsu 525-8577, Japan.
Luthfia DewiLaboratory of Exercise Biochemistry, University of Taipei, New Taipei City 11153, Taiwan.
Yu-Chieh LiaoLaboratory of Exercise Biochemistry, University of Taipei, New Taipei City 11153, Taiwan.
Chih-Yang HuangCardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien 970, Taiwan.
Chia-Hua KuoLaboratory of Exercise Biochemistry, University of Taipei, New Taipei City 11153, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Higher intensity exercise, despite causing more tissue damage, improved aging conditions. We previously observed decreased p16

Indexed as

Anti-Inflammatory Agents, Non-SteroidalCross-Over StudiesIbuprofenInflammationMuscle, SkeletalAdultCD11b AntigenCyclin-Dependent Kinase Inhibitor p16ExerciseHigh-Intensity Interval TrainingHumansMaleRNA, MessengerYoung AdultAnti-Inflammatory Agents, Non-SteroidalCD11b AntigenCyclin-Dependent Kinase Inhibitor p16IbuprofenITGAM protein, humanRNA, Messengercellular senescencehigh-intensity intermittent exerciseinflammationNSAIDp16INK4a

Identifiers

PMID38752873
PMCPMC11164480

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.