Evidence map›Paper›PMID 38752802›Full record

ArticleHuman vaccines & immunotherapeutics2024

Antibody persistence to diphtheria toxoid, tetanus toxoid,

Nasamon Wanlapakorn, Nasiri Sarawanangkoor, Donchida Srimuan, Thaksaporn Thatsanathorn, Thanunrat Thongmee, Yong Poovorawan

Registry-linked trialAbstract readComparative Study
In one paragraph

Article in Human vaccines & immunotherapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02408926 (Vaccine Responses in Infants After Acellular Pertussis Vaccination During Pregnancy in Thailand), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02408926 phase4completednot on this map

Vaccine Responses in Infants After Acellular Pertussis Vaccination During Pregnancy in Thailand

TypeinterventionalSponsorUniversiteit AntwerpenRan2015 to 2018Enrolled370ConditionsPertussisArmsBoostrix, Infanrix hexa, Quinvaxem, OPV
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nasamon WanlapakornCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Nasiri SarawanangkoorCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Donchida SrimuanCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Thaksaporn ThatsanathornCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Thanunrat ThongmeeCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Yong PoovorawanCenter of Excellence in Clinical Virology, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.ORCID 0000-0002-2337-6807

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thailand has incorporated the whole-cell (wP) pertussis vaccine into the expanded program on immunization since 1977 and has offered the acellular pertussis (aP) vaccine as an optional vaccine for infants since 2001. We followed healthy children from a clinical trial (ClinicalTrials.gov NCT02408926) in which children were randomly assigned to receive either pentavalent (DTwP-HB-Hib) or hexavalent (DTaP-IPV-HB-Hib) vaccines for their primary series (administered at 2, 4, and 6 months) and first booster vaccination (18 months). Both groups received Tdap-IPV as a second booster at the age of 4 y. Blood samples were collected for evaluation of antibody persistence to diphtheria toxoid (DT), tetanus toxoid (TT), and

Indexed as

Antibodies, BacterialBordetella pertussisDiphtheria-Tetanus-Pertussis VaccineHaemophilus influenzae type bHaemophilus VaccinesImmunization, SecondaryVaccines, CombinedWhooping CoughChild, PreschoolDiphtheriaDiphtheria-Tetanus-acellular Pertussis VaccinesDiphtheria ToxoidFemaleFollow-Up StudiesHaemophilus InfectionsHumansAntibodies, BacterialDiphtheria-Tetanus-acellular Pertussis VaccinesDiphtheria-Tetanus-Pertussis VaccineDiphtheria ToxoidHaemophilus VaccinesPoliovirus Vaccine, InactivatedTetanus ToxoidVaccines, CombinedacellularchildhoodDiphtheriaHaemophilus influenzae type bpertussistetanusvaccine antibodywhole cell

Identifiers

PMID38752802
PMCPMC11789732

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.