Evidence map›Paper›PMID 38752558›Full record

Trial reportAIDS (London, England)2024

An agricultural livelihood intervention is associated with reduced HIV stigma among people with HIV.

Sheri D Weiser, Lila A Sheira, Elly Weke, Jennifer M Zakaras, Pauline Wekesa, Edward A Frongillo, Rachel L Burger, Adrienne Rain Mocello, Harsha Thirumurthy, Shari L Dworkin and 5 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in AIDS (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sheri D WeiserDepartment of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Lila A SheiraDepartment of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Elly WekeCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Jennifer M ZakarasDepartment of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Pauline WekesaCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Edward A FrongilloDepartment of Health Promotion, Education, and Behavior, Arnold School of Public Health, Discovery I, University of South Carolina, Columbia, SC.
Rachel L BurgerDepartment of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, San Francisco, CA.
Adrienne Rain MocelloDepartment of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Harsha ThirumurthyDepartment of Medical Ethics and Health Policy, Perelman School of Medicine, University of Pennsylvania, Blockley Hall, Philadelphia, PA.
Shari L DworkinSchool of Nursing and Health Studies, University of Washington Bothell, Bothell, WA.
Alexander C TsaiCenter for Global Health and Mongan Institute, Massachusetts General Hospital, Boston, MA.
James G KahnDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA.
Lisa M ButlerInstitute for Collaboration on Health, Intervention, and Policy, University of Connecticut, Storrs, CT, USA.
Elizabeth A BukusiCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, Kenya.
Craig R CohenDepartment of Obstetrics, Gynecology & Reproductive Sciences, University of California, San Francisco, San Francisco, CA.

Funding

Agricultural intervention for food security and HIV healthoutcomes in KenyaR01MH107330 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COHEN, CRAIG R, WEISER, SHERI DAWN · 2015 to 2019
$4.7M
Sustainable Development for Improved HIV Health and Prevention in Kenya (SD4H-Kenya)D43TW011306 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BUKUSI, ELIZABETH ANNE, COHEN, CRAIG R · 2020 to 2024
$1.9M
Mentoring in Patient Oriented Research on Food Insecurity, HIV and AgingK24AI134326 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SHERI Dawn WEISER · 2017 to 2026
$1.4M
FIC NIH HHS D43 TW011306NIAID NIH HHS K24 AI134326NIMH NIH HHS R01 MH107330
6 · The paper itself

Abstract

objectiveHIV stigma undermines antiretroviral treatment (ART) adherence and viral suppression. Livelihood interventions may target drivers of negative attitudes towards people with HIV (PWH) by improving their health and strengthening their economic contributions. We examined the effects of a multisectoral agricultural livelihood intervention on HIV stigma among PWH in western Kenya.

designSixteen health facilities were randomly allocated (1 : 1) to intervention or control arms in Shamba Maisha , a cluster randomized controlled trial that aimed to improve HIV-related health through behavioral, mental health, and nutritional pathways.

methodsThe intervention included a farming loan and agricultural and financial training. Participants had access to farmland and surface water and were at least 18 years old, on ART for more than 6 months, and moderately-to-severely food insecure. We measured internalized, anticipated, and enacted HIV stigma semiannually over 2 years using validated scales. In blinded intent-to-treat analyses, we compared changes in scores over 24 months by study arm, using longitudinal multilevel difference-in-differences linear regression models that accounted for clustering.

resultsOf 720 enrolled participants (354 intervention), 55% were women, and the median age was 40 years [interquartile range 34-47 years]. Two-year retention was 94%. Compared with the control arm, the intervention resulted in significant decreases ( P  < 0.001) of 0.42 points [95% confidence interval (CI) -0.52 to -0.31) in internalized stigma, 0.43 points (95% CI -0.51 to -0.34) in anticipated stigma, and 0.13 points (95% CI -0.16 to -0.09) in enacted stigma over 24 months.

conclusionThe agricultural livelihood intervention reduced HIV stigma among PWH. Poverty-reduction approaches may be a novel strategy for reducing HIV stigma.

Indexed as

HIV InfectionsSocial StigmaAdultAgricultureDrug MonitoringFemaleHumansKenyaMaleMedication AdherenceMiddle AgedYoung Adult

Identifiers

PMID38752558
PMCPMC12439198

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.