Evidence map›Paper›PMID 38752418›Full record

Trial reportChronic respiratory disease

Effects of a respiratory and neurological rehabilitation treatment plan in post Covid-19 affected university students. Randomized clinical study.

Zacarías Sánchez Milá, David Rodríguez Sanz, Ana Martín Nieto, Ana Jiménez Lobo, Manuel Ramos Hernández, Angélica Campón Chekroun, Raúl Frutos Llanes, José Manuel Barragán Casas, Jorge Velázquez Saornil

2 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Chronic respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05195099 nacompletednot on this map

Effectiveness of a Physiotherapy Respiratory and Neurorehabilitation Treatment Protocol in Patients With COVID-19.

TypeinterventionalSponsorUniversidad Católica de ÁvilaRan2022 to 2022Enrolled200ConditionsCOVID-19 PandemicArmsrespiratory treatment
NCT07204431 nacompletednot on this map

Efficacy of Respiratory Physiotherapy Treatment in Patients With Chronic Obstructive Disease in Elderly Patients.

TypeinterventionalSponsorUniversidad Católica de ÁvilaRan2025 to 2025Enrolled60ConditionsChronic Obstructive Pulmonary DiseaseArmsthe PowerBreathe and PEP Therosold tools group.
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Assessment and management of post-COVID-19 pulmonary complications: a rapid review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zacarías Sánchez MiláNEUMUSK Group Research, Department of Physiotherapy, Facultad de Ciencias de La Salud, Universidad Católica de Ávila, Ávila, Spain.ORCID 0000-0002-4129-2084
David Rodríguez SanzFaculty of Nursing, Physiotherapy and Podiatry Universidad Complutense of Madrid, Madrid, Spain.
Ana Martín NietoSan Juan de Dios Foundation, Madrid, Spain.
Ana Jiménez LoboNEUMUSK Group Research, Department of Physiotherapy, Facultad de Ciencias de La Salud, Universidad Católica de Ávila, Ávila, Spain.
Manuel Ramos HernándezNEUMUSK Group Research, Department of Physiotherapy, Facultad de Ciencias de La Salud, Universidad Católica de Ávila, Ávila, Spain.
Angélica Campón ChekrounNEUMUSK Group Research, Department of Physiotherapy, Facultad de Ciencias de La Salud, Universidad Católica de Ávila, Ávila, Spain.
Raúl Frutos LlanesNEUMUSK Group Research, Department of Physiotherapy, Facultad de Ciencias de La Salud, Universidad Católica de Ávila, Ávila, Spain.
José Manuel Barragán CasasNEUMUSK Group Research, Department of Physiotherapy, Facultad de Ciencias de La Salud, Universidad Católica de Ávila, Ávila, Spain.
Jorge Velázquez SaornilNEUMUSK Group Research, Department of Physiotherapy, Facultad de Ciencias de La Salud, Universidad Católica de Ávila, Ávila, Spain.ORCID 0000-0003-2608-2019

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 demonstrated the possibility of neurological complications such as loss of sense of smell and taste, together with respiratory problems. Respiratory training and rehabilitation of neurological sequelae are essential to improve respiratory function and thus quality of life, and the aim of this study is to evaluate the efficacy of a pulmonary and neurological rehabilitation program.

objectivesTo apply a treatment to reduce dyspnea, increase exertional capacity, increase vital capacity and respiratory muscle strength, together with an increase in olfactory and gustatory sensitivity in post-SARS-CoV-2 patients.

methodsA randomised controlled experimental study was conducted in 220 patients with a medical diagnosis of COVID-19 and more than 5 months of evolution, dyspnoea or perceived fatigue, including olfactory and gustatory perception problems, of whom 200 patients completed the study. 100 patients were randomly assigned to the intervention group, consisting of an inspiratory training treatment plan (Powerbreathe Plus®) combined with aerobic exercise and olfactory gustatory treatment for 31 days, and 100 patients to the control group, for 31 days without any type of therapy.

resultsThe study was conducted in post-Covid-19 patients for 5 months. Two hundred patients were divided into an intervention group (

conclusionThe implementation of a respiratory rehabilitation treatment plan with the Powerbreathe Plus® device, aerobic exercise and neurorehabilitation with olfactory and gustatory training, is a therapeutic option against respiratory and neurological sequelae in patients who have suffered such sequelae due to the SARS-CoV-2 virus. Clinicaltrials.gov: NCT05195099. First posted 18/01/2022; Last Update Posted 29/06/2022.

Indexed as

COVID-19AdultBreathing ExercisesDyspneaExercise TherapyFemaleHumansMaleMuscle StrengthNeurological RehabilitationOlfaction DisordersQuality of LifeSARS-CoV-2StudentsUniversitiesVital CapacityCovid-19dysphoneaneurorehabilitationphysiotherapyrespiratory therapy

Identifiers

PMID38752418
PMCPMC11100389

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.