Evidence map›Paper›PMID 38751955›Full record

ArticleBJUI compass2024

A preoperative magnetic resonance imaging can aid in staging and treatment choice for upper tract urothelial carcinoma.

Bjarte Almås, Lars Anders Rokne Reisæter, Carl Erik Markhus, Karin Margrethe Hjelle, Astrid Børretzen, Christian Beisland

Erratum issuedAbstract read
In one paragraph

Article in BJUI compass, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Erratum.BJUI compass · 2024
    Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Bjarte AlmåsDepartment of Urology Haukeland University Hospital Bergen Norway.ORCID https://orcid.org/0000-0003-4484-040X
Lars Anders Rokne ReisæterDepartment of Radiology Haukeland University Hospital Bergen Norway.
Carl Erik MarkhusDepartment of Radiology Haukeland University Hospital Bergen Norway.
Karin Margrethe HjelleDepartment of Urology Haukeland University Hospital Bergen Norway.
Astrid BørretzenDepartment of Pathology Haukeland University Hospital Bergen Norway.
Christian BeislandDepartment of Urology Haukeland University Hospital Bergen Norway.ORCID https://orcid.org/0000-0002-3216-4937

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The aim was to investigate the predictive abilities of a preoperative diffusion-weighted MRI (dwMRI) among patients with surgically treated upper tract urothelial carcinoma (UTUC). Materials and methods: Written consent was obtained from all participants in this prospective and ethically approved study. Thirty-five UTUC patients treated with radical surgery were examined with a preoperative dwMRI and prospectively included during 2017-2022. Two radiologists examined the CT scans and dwMRIs for radiological stage, and the apparent diffusion coefficient (ADC) in the tumours at the dwMRI was registered. The radiologists were blinded for patient history, final histopathology and the readings of the other radiologist. The radiological variables were analysed regarding their abilities to predict muscle-invasive disease (MID, T2-T4) and tumour grade at final pathology after radical surgery. The predictive abilities were assessed using chi-square tests, Student's Results: Mean age was 72 years, 20 had high-grade tumour, and 13 patients had MID. The ADC values at the dwMRI were significantly lower among patients with MID compared to patients with non-muscle-invasive disease (930 vs 1189, Conclusion: Tumour ADC at the MRI emerges as a potential biomarker for aggressive disease. The results are promising but should be validated in a larger, multicentre study.

Indexed as

diagnosisMRIprospective studystagingupper tract urothelial carcinoma

Identifiers

PMID38751955
PMCPMC11090765

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.