Evidence map›Paper›PMID 38751756›Full record

ArticleTherapeutic advances in infectious disease

Examining biopsychosocial predictors of risk for cognitive impairment among a racially diverse sample of men who have sex with men living with HIV.

Casey D Xavier Hall, Beth Okantey, Zhuo Meng, Crim Sabuncu, Brittany Lane, Eugenia Millender, Artur Queiroz, Jung Hyo Kim, Lorie Okada, Avrum Gillespie and 4 more

Abstract read
In one paragraph

Article in Therapeutic advances in infectious disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Casey D Xavier HallCenter of Population Sciences for Health Equity, College of Nursing, Florida State University, 2010 Levy Avenue, Innovation Park, Building B, Suite 3600, Tallahassee, FL 32310, USA.ORCID https://orcid.org/0000-0003-1658-3717
Beth OkanteyCenter of Population Sciences for Health Equity, College of Nursing, Florida State University, Tallahassee, FL, USA.
Zhuo MengCenter of Population Sciences for Health Equity, College of Nursing, Florida State University, Tallahassee, FL, USA.
Crim SabuncuCenter of Population Sciences for Health Equity, College of Nursing, Florida State University, Tallahassee, FL, USA.
Brittany LaneCenter of Population Sciences for Health Equity, College of Nursing, Florida State University, Tallahassee, FL, USA.
Eugenia MillenderCenter of Population Sciences for Health Equity, College of Nursing, Florida State University, Tallahassee, FL, USA.
Artur QueirozCenter of Population Sciences for Health Equity, College of Nursing, Florida State University, Tallahassee, FL, USA.ORCID https://orcid.org/0000-0002-6350-1908
Jung Hyo KimCenter of Population Sciences for Health Equity, College of Nursing, Florida State University, Tallahassee, FL, USA.
Lorie OkadaUniversity of Hawaii, Manoa, Honolulu, HI, USA.
Avrum GillespieDepartment of Medicine, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
Gina SimonciniCenter of Asian Health, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
John 'Jack' P BarileUniversity of Hawaii, Manoa, Honolulu, HI, USA.
Grace X MaCenter of Asian Health, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, USA.
Frank 'Frankie' Y WongCenter of Population Sciences for Health Equity, College of Nursing, Florida State University, Tallahassee, FL, USA.

Funding

The Role of gp120 on Cardiovascular Disease in People Living with HIVU54MD007601 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI Kathryn Lenzner Braun · 2017 to 2026
$59.5M
Unpacking the Mechanisms of Disparities for HIV-related Hypertension in African American and Asian Pacific American MSMR01MD013501 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI MA, GRACE X., WONG, FRANK Y. · 2018 to 2022
$3.5M
NHLBI NIH HHS L60 HL170367NIMHD NIH HHS R01 MD013501NIMHD NIH HHS U54 MD007601
6 · The paper itself

Abstract

Background: Cognitive decline among people living with HIV (PLWH) is growing concern as world populations become increasing older including higher proportions of PLWH. It is vitally important to understand psychosocial predictors of age-related cognitive decline men who have sex with men (MSM) living with HIV. Objectives: The current study seeks to examine psychosocial risk factors the contribute to the risk of age-related cognitive impairment as measured by Cardiovascular Risk Factors, Aging, and Incidence of Dementia (CAIDE) score in a racially diverse sample of MSM living with HIV. Design: The present analysis utilizes data from the baseline ( Methods: Using a self-report survey, we examine the associations between psychosocial predictors (e.g. trauma, mental health, chronic pain, sleep disturbance, etc.) and risk of dementia using the CAIDE risk score. Analyses include linear and logistic regression. Results: In adjusted model stress, chronic pain, Black racial identity, and having a sexual identity that is bisexual or another category are all positively associated with CAIDE scores. Childhood sexual abuse history was negatively associated with CAIDE scores indicating a protective effect. Sleep disorder has a positive association with CAIDE scores after adjusting for the baseline CAIDE scores. Conclusion: These results indicate modifiable correlates of cognitive risk (stress and chronic pain). Interventions should seek to address these comorbid factors including the consideration of minority stress and stigma. Interventions should seek to reach Black and bisexual men living with HIV, including possible cultural tailoring to interventions and messaging. Lastly, future research should examine the impact of variation within childhood sexual abuse histories to better understand their association with cognitive impairment later in life. This may include considering the nature, severity, and potential treatment of trauma symptoms.

Indexed as

agingcardiovascularcognitive impairmentHIVmen who have sex with men

Identifiers

PMID38751756
PMCPMC11095190

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.