Evidence map›Paper›PMID 38751644›Full record

ArticleACS pharmacology & translational science2024

Degradation of the α-Carboxyl Terminus 11 Peptide:

Yagmur Tasdemiroglu, McAlister Council-Troche, Miao Chen, Benjamin Ledford, Russell A Norris, Steven Poelzing, Robert G Gourdie, Jia-Qiang He

Abstract read
In one paragraph

Article in ACS pharmacology & translational science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yagmur TasdemirogluDepartment of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Tech, 225 Duck Pond Drive, Blacksburg, Virginia 24061, United States.
McAlister Council-TrocheDepartment of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Tech, 225 Duck Pond Drive, Blacksburg, Virginia 24061, United States.
Miao ChenDepartment of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Tech, 225 Duck Pond Drive, Blacksburg, Virginia 24061, United States.
Benjamin LedfordDepartment of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Tech, 225 Duck Pond Drive, Blacksburg, Virginia 24061, United States.
Russell A NorrisDepartment of Medicine, Medical University of South Carolina, Charleston, South Carolina 29425, United States.
Steven PoelzingCenter for Vascular and Heart Research, Fralin Biomedical Research Institute, Virginia Tech, 2 Riverside Circle, Roanoke, Virginia 24016, United States.
Robert G GourdieCenter for Vascular and Heart Research, Fralin Biomedical Research Institute, Virginia Tech, 2 Riverside Circle, Roanoke, Virginia 24016, United States.ORCID https://orcid.org/0000-0001-6021-0796
Jia-Qiang HeDepartment of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Tech, 225 Duck Pond Drive, Blacksburg, Virginia 24061, United States.ORCID https://orcid.org/0000-0002-0640-5960

Funding

PATTERNING OF GAP JUNCTION COUPLING IN DEVELOPING HEARTR01HL056728 · NHLBI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI GOURDIE, ROBERT G · 1997 to 2021
$5.6M
Connexin-based Signaling in the Heart: Cellular and ExosomalR35HL161237 · NHLBI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI ROBERT G GOURDIE · 2022 to 2026
$4.4M
Cilia and Valvular Heart DiseaseR01HL131546 · NHLBI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI NORRIS, RUSSELL · 2016 to 2025
$4.4M
Arrhythmia Mechanisms Modulated by Intercalated Disc Extracellular NanodomainsR01HL159097 · NHLBI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI Steven Poelzing · 2023 to 2026
$2.5M
Dzip1 and Mitral Valve ProlapseR01HL149696 · NHLBI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI NORRIS, RUSSELL · 2020 to 2023
$2.0M
The Role of the Sodium Channel Beta Subunit in Cardiac ConductionR01HL141855 · NHLBI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI GOURDIE, ROBERT G, POELZING, STEVEN · 2018 to 2021
$1.8M
Meis1 Negatively Regulates Blood Flow in Hindlimb IschemiaR15HL140528 · NHLBI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI HE, JIA-QIANG · 2018 to 2018
$483k
Development of an Intravenously Delivered Nanofiber to Target MMP-2 in Aortic AneurysmsF32HL156515 · NHLBI · UNIVERSITY OF VIRGINIA · PI LEDFORD, BENJAMIN · 2022 to 2025
$247k
NHLBI NIH HHS F32 HL156515NHLBI NIH HHS R01 HL056728NHLBI NIH HHS R01 HL131546NHLBI NIH HHS R01 HL141855NHLBI NIH HHS R01 HL149696NHLBI NIH HHS R01 HL159097NHLBI NIH HHS R15 HL140528NHLBI NIH HHS R35 HL161237
6 · The paper itself

Abstract

In previous research, a synthetic α-carboxyl terminus 1 (αCT1) peptide derived from connexin 43 (Cx43) and its variant (αCT11) showed beneficial effects in an

Identifiers

PMID38751644
PMCPMC11091968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.