Evidence map›Paper›PMID 38751639›Full record

ArticleACS pharmacology & translational science2024

Coumarin-Furoxan Hybrid Suppressed the Proliferation and Metastasis of Triple-Negative Breast Cancer by Activating Mitochondrial Stress and Cell Apoptosis.

Mengru Li, Fan Cao, Weijie Wang, Yulei Ma, Zhihui Yu, Ke Wang, Ying Chen, Hongrui Liu

Abstract read
In one paragraph

Article in ACS pharmacology & translational science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mengru LiDepartment of Pharmacology, School of Pharmacy, Fudan University, Shanghai 201203, China.ORCID https://orcid.org/0000-0003-2697-4615
Fan CaoDepartment of Pharmacology, School of Pharmacy, Fudan University, Shanghai 201203, China.
Weijie WangDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 201203, China.
Yulei MaDepartment of Pharmacology, School of Pharmacy, Fudan University, Shanghai 201203, China.
Zhihui YuDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 201203, China.
Ke WangDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 201203, China.
Ying ChenDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai 201203, China.ORCID https://orcid.org/0000-0002-8197-3108
Hongrui LiuDepartment of Pharmacology, School of Pharmacy, Fudan University, Shanghai 201203, China.ORCID https://orcid.org/0000-0003-3975-8196

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) typically manifests as higher invasive carcinoma correlated with a worse prognosis that primarily relies on chemotherapy. There is growing evidence that nitric oxide (NO) donor drugs have the potential for anticancer therapy. On this basis, we constructed and evaluated a novel coumarin-furoxan hybrid

Identifiers

PMID38751639
PMCPMC11091983

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.