Evidence map›Paper›PMID 38751563›Full record

ArticleBritish journal of pain2024

A rapid systematic review of breakthrough pain definitions and descriptions.

Katie Greenfield, Daniel E Schoth, Richard Hain, Simon Bailey, Christine Mott, Dilini Rajapakse, Emily Harrop, Kate Renton, Anna-Karenia Anderson, Bernie Carter and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in British journal of pain, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06790719 (Development and Validation of a Paediatric Breakthrough Pain Assessment Tool), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06790719 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Development and Validation of a Paediatric Breakthrough Pain Assessment Tool

TypeobservationalSponsorUniversity of SouthamptonRan2025 to 2025Enrolled210ConditionsBreakthrough Pain, Palliative Medicine, Oncology Pain, Pediatric ALL
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Breakthrough cancer pain management (BTcP)-gap analysis of the current Australian landscape.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Katie GreenfieldSchool of Psychology, University of Southampton, Highfield, UK.
Daniel E SchothSchool of Psychology, University of Southampton, Highfield, UK.
Richard HainPaediatric Palliative Medicine, Noah's Ark Children's Hospital for Wales, Cardiff, UK.ORCID https://orcid.org/0000-0001-5838-1713
Simon BaileySir James Spence Institute,Royal Victoria Infirmary, Newcastle upon Tyne,UK.
Christine MottAcorns Children's Hospice, Birmingham,UK.
Dilini RajapakseGreat Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Emily HarropHelen & Douglas House Hospices, Oxford, UK.
Kate RentonUniversity Hospital Southampton NHS Trust, Southampton General Hospital, Southampton, UK.
Anna-Karenia AndersonRoyal Marsden Hospital, Sutton, UK.
Bernie CarterFaculty of Health, Social Care and Medicine,Edge Hill University, Ormskirk, UK.
Margaret JohnsonPatient & Public Representative,London,UK.
Christina LiossiSchool of Psychology, University of Southampton, Highfield, UK.ORCID https://orcid.org/0000-0003-0627-6377

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Breakthrough pain is common in life-limiting conditions and at end-of-life. Despite over 30 years of study, there is little consensus regarding the definition and characteristics of breakthrough pain. Objective: This study aims to update and expand a 2010 systematic review by Haugen and colleagues to identify (1) all definitions of breakthrough pain and (2) all descriptions and classifications of breakthrough pain reported by patients, caregivers, clinicians, and experts. Design: This rapid systematic review followed the Cochrane Rapid Review Methods Group guidelines. A protocol is published on PROSPERO (CRD42019155583). Data sources: CINAHL, MEDLINE, PsycINFO, and the Web of Science were searched for breakthrough pain terms from the inception dates of each database to 26th August 2022. Results: We identified 65 studies that included data on breakthrough pain definitions, descriptions, or classifications from patients ( Conclusions: Despite ongoing efforts, there is still no consensus on the definition of breakthrough pain. A compromise is needed on breakthrough pain nomenclature to collect reliable incidence and prevalence data and to inform further refinement of the construct.

Indexed as

Breakthrough painpain classificationsystematic review

Identifiers

PMID38751563
PMCPMC11092936

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.