ArticleEuropean heart journal open2024
Sex-specific cardiac magnetic resonance pulmonary capillary wedge pressure.
Article in European heart journal open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- MRI staging of haemodynamic congestion and clinical outcomes.European radiology · 2026Article
- Prognostic Value of Left-Ventricular Filling Pressure Estimated by Cardiovascular Magnetic Resonance in Patients With Acute ST-Segment Elevation Myocardial Infarction.Reviews in cardiovascular medicine · 2026Article
- Non-invasive cardiovascular magnetic resonance pulmonary capillary wedge pressure predicts future atrial fibrillation: a LOOP substudy.ESC heart failure · 2026Article
- Observational
- Development and Validation of a Noninvasive Model of Mixed Venous Oxygen Saturation in Heart Failure.JACC. Advances · 2026Article
- Cardiovascular magnetic resonance in contemporary guidelines: divergence between ESC and NICE across major cardiovascular diseases.European heart journal. Imaging methods and practice · 2026Review
- Evaluating biventricular diastolic function using cardiovascular magnetic resonance 4d-flow derived E/e'.European heart journal. Imaging methods and practice · 2026Article
- Beyond volumes and ejection fraction: practical insights into cine-CMR interpretation and applications.The international journal of cardiovascular imaging · 2025Review
- Haemodynamic implications of cardiovascular magnetic resonance pulmonary capillary wedge pressure in acute myocardial infarction.European heart journal. Imaging methods and practice · 2025Article
- CMR Left Ventricular Filling Pressure Exhibits Strong Haemodynamic Relevance and Outperforms Echocardiography in Multimodal Heart Failure Assessment.Journal of cardiovascular development and disease · 2025Article
- Cardiac magnetic resonance left atrioventricular coupling index as a prognostic tool in hypertrophic cardiomyopathy.ESC heart failure · 2025Article
- Risk factors for raised left ventricular filling pressure by cardiovascular magnetic resonance: Prognostic insights.ESC heart failure · 2024Article
- Improved Interpretation of Pulmonary Artery Wedge Pressures through Left Atrial Volumetry-A Cardiac Magnetic Resonance Imaging Study.Journal of cardiovascular development and disease · 2024Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Aims: Heart failure (HF) with preserved ejection fraction disproportionately affects women. There are no validated sex-specific tools for HF diagnosis despite widely reported differences in cardiac structure. This study investigates whether sex, as assigned at birth, influences cardiac magnetic resonance (CMR) assessment of left ventricular filling pressure (LVFP), a hallmark of HF agnostic to ejection fraction. Methods and results: A derivation cohort of patients with suspected pulmonary hypertension and HF from the Sheffield centre underwent invasive right heart catheterization and CMR within 24 h of each other. A sex-specific CMR model to estimate LVFP, measured as pulmonary capillary wedge pressure (PCWP), was developed using multivariable regression. A validation cohort of patients with confirmed HF from the Leeds centre was used to evaluate for the primary endpoints of HF hospitalization and major adverse cardiovascular events (MACEs). Comparison between generic and sex-specific CMR-derived PCWP was undertaken. A total of 835 (60% female) and 454 (36% female) patients were recruited into the derivation and validation cohorts respectively. A sex-specific model incorporating left atrial volume and left ventricular mass was created. The generic CMR PCWP showed significant differences between males and females (14.7 ± 4 vs. 13 ± 3.0 mmHg, Conclusion: Accounting for sex improves precision and prognostic performance of CMR biomarkers for HF.
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Registered trials
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