Evidence map›Paper›PMID 38751437›Full record

ArticleChinese journal of cancer research = Chung-kuo yen cheng yen chiu2024

New roles of tumor-derived exosomes in tumor microenvironment.

Shiqian Chen, Jinzhe Sun, Huan Zhou, Hongbin Lei, Dan Zang, Jun Chen

Abstract read
In one paragraph

Article in Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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  20. Exosomal ncRNAs in reproductive cancers†.Biology of reproduction · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shiqian ChenDepartment of Oncology, the Second Hospital of Dalian Medical University, Dalian 116023, China.
Jinzhe SunDepartment of Oncology, the Second Hospital of Dalian Medical University, Dalian 116023, China.
Huan ZhouDepartment of Oncology, the Second Hospital of Dalian Medical University, Dalian 116023, China.
Hongbin LeiDepartment of Radiotherapy, the Second Hospital of Dalian Medical University, Dalian 116023, China.
Dan ZangDepartment of Oncology, the Second Hospital of Dalian Medical University, Dalian 116023, China.
Jun ChenDepartment of Oncology, the Second Hospital of Dalian Medical University, Dalian 116023, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Throughout tumorigenesis, the co-evolution of tumor cells and their surrounding microenvironment leads to the development of malignant phenotypes. Cellular communication within the tumor microenvironment (TME) plays a critical role in influencing various aspects of tumor progression, including invasion and metastasis. The release of exosomes, a type of extracellular vesicle, by most cell types in the body, is an essential mediator of intercellular communication. A growing body of research indicates that tumor-derived exosomes (TDEs) significantly expedite tumor progression through multiple mechanisms, inducing epithelial-mesenchymal transition and macrophage polarization, enhancing angiogenesis, and aiding in the immune evasion of tumor cells. Herein, we describe the formation and characteristics of the TME, and summarize the contents of TDEs and their diverse functions in modulating tumor development. Furthermore, we explore potential applications of TDEs in tumor diagnosis and treatment.

Indexed as

diagnosistreatmentTumor-derived exosomestumorigenesistumor microenvironment

Identifiers

PMID38751437
PMCPMC11090792

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.