Evidence map›Paper›PMID 38751054›Full record

ArticleInternational journal of aging & human development2025

Moving Beyond Depression: Mood Symptoms Across the Spectrum Relate to Tau Pathology in Older Women at Risk for Alzheimer's Disease.

Nargis Ahmadi, Melanie A Dratva, Nadine Heyworth, Xin Wang, Kaj Blennow, Sarah J Banks, Erin E Sudermann

Abstract read
In one paragraph

Article in International journal of aging & human development, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nargis AhmadiUniversity of California, San Diego, USA.ORCID 0000-0002-8786-7277
Melanie A DratvaDepartment of Neurosciences, University of California, San Diego, USA.
Nadine HeyworthDepartment of Neurosciences, University of California, San Diego, USA.
Xin WangDepartment of Neurosciences, University of California, San Diego, USA.
Kaj BlennowDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, University of Gothenburg, Mölndal, Sweden.
Sarah J BanksDepartment of Neurosciences, University of California, San Diego, USA.
Erin E SudermannDepartment of Psychiatry, University of California, San Diego, USA.

Funding

Biological and lifestyle factors contributing to Tau in women at risk for Alzheimer's disease.R01AG080663 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SARAH BANKS, Erin elizabeth Sundermann · 2023 to 2026
$4.2M
The MADURA Program: Mentorship for Advancing Diversity in Undergraduate Research on AgingR25AG066594 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Steven Dyal Edland · 2020 to 2026
$2.5M
NIA NIH HHS R01 AG080663NIA NIH HHS R25 AG066594
6 · The paper itself

Abstract

We examined how symptoms across the mood spectrum relate to Alzheimer's disease (AD) biomarkers in older women at high risk for AD. Participants included 25 women aged 65+ with mild cognitive deficits and elevated AD genetic risk. The Profile of Mood States Questionnaire measured mood symptoms and a total mood disturbance (TMD) score. Tau burden in the meta-temporal region of interest was measured using MK-6240 Tau positron emission tomography (PET) imaging. A subset (

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesPositron-Emission Tomographytau ProteinsAffectAgedAged, 80 and overBiomarkersCognitive DysfunctionDepressionFemaleHumansAmyloid beta-PeptidesBiomarkerstau ProteinsAlzheimer's diseasedementiamood symptomstau pathology

Identifiers

PMID38751054
PMCPMC12036793

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.