Evidence map›Paper›PMID 38750497›Full record

ArticleMicrobial cell factories2024

Enhancement of vitamin B

Zhizhong Tian, Linxia Liu, Lijuan Wu, Zixuan Yang, Yahui Zhang, Liping Du, Dawei Zhang

Erratum issuedAbstract read
In one paragraph

Article in Microbial cell factories, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Enhanced vitamin BSynthetic and systems biotechnology · 2026
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Zhizhong Tian *College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, China.
Linxia Liu *Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Lijuan WuTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Zixuan YangTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Yahui ZhangTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China.
Liping DuCollege of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, China. dlp123@tust.edu.cn.
Dawei ZhangTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, 300308, China. zhang_dw@tib.cas.cn.

Funding

National Key Research and Development Program of China 2022YFC2106100National Natural Science Foundation of China 22178372, 32200049National Science Fund for Distinguished Young Scholars 22325807Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project TSBICIP-KJGG-011, TSBICIP-CXRC-055Yellow River Delta Industry Leading Talents DYRC20190212
6 · The paper itself

Abstract

backgroundMicrobial engineering aims to enhance the ability of bacteria to produce valuable products, including vitamin B

resultsIn this study, we conducted transcriptome and metabolome analyses to investigate the effects of the accumulation of pyridoxine, which is the major commercial form of vitamin B

conclusionOur results provide insights into pyridoxine biosynthesis within the cellular metabolic network for the first time. Our comprehensive analysis revealed that the fermentation process resulted in a remarkable final yield of 1.95 g/L pyridoxine, the highest reported yield to date. This work lays a foundation for the green industrial production of vitamin B

Indexed as

Escherichia coliFermentationPyridoxineVitamin B 6Amino AcidsCarbonCitric Acid CycleMetabolic EngineeringMetabolic Networks and PathwaysMetabolomeMetabolomicsNitrogenTranscriptomeAmino AcidsCarbonNitrogenPyridoxineVitamin B 6Cellular processesFermentation optimizationOmics analysisVitamin B6

Identifiers

PMID38750497
PMCPMC11095007

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.