Evidence map›Paper›PMID 38750492›Full record

ArticleRespiratory research2024

The prevalence and mortality risks of PRISm and COPD in the United States from NHANES 2007-2012.

Christopher J Cadham, Hayoung Oh, MeiLan K Han, David Mannino, Steven Cook, Rafael Meza, David T Levy, Luz María Sánchez-Romero

Abstract read
In one paragraph

Article in Respiratory research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christopher J Cadham *School of Public Health, Department of Health Management and Policy, University of Michigan, Ann Arbor, MI, USA.
Hayoung Oh *Georgetown University-Lombardi Comprehensive Cancer Center, Washington, DC, USA.
MeiLan K HanDivision of Pulmonary and Critical Care, University of Michigan Health System, Ann Arbor, MI, USA.
David ManninoDivision of Pulmonary and Critical Care Medicine, University of Kentucky, Lexington, KY, USA.
Steven CookSchool of Public Health, Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.
Rafael MezaBC Cancer Research Institute, Vancouver, Canada.
David T LevyGeorgetown University-Lombardi Comprehensive Cancer Center, Washington, DC, USA.
Luz María Sánchez-RomeroGeorgetown University-Lombardi Comprehensive Cancer Center, Washington, DC, USA. ls1364@georgetown.edu.

Funding

Research Project 3: Modeling the Impact of Tobacco Control Policies on Polytobacco Use and Associated Health DisparitiesU54CA229974 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Abigail S. Friedman · 2018 to 2026
$39.2M
Modeling the impact of tobacco regulations on US future trends of Chronic Obstructive Pulmonary Disease.K01CA260378 · NCI · GEORGETOWN UNIVERSITY · PI SANCHEZ-ROMERO, LUZ MARIA · 2021 to 2025
$775k
CIHR DFD - 187708NCI NIH HHS K01 CA260378NCI NIH HHS K01CA260378NCI NIH HHS U54 CA229974NCI NIH HHS U54CA229974Pharmaceutical Research and Manufacturers of America Foundation AWD024330
6 · The paper itself

Abstract

backgroundWe estimated the prevalence and mortality risks of preserved ratio impaired spirometry (PRISm) and chronic obstructive pulmonary disease (COPD) in the US adult population.

methodsWe linked three waves of pre-bronchodilator spirometry data from the US National Health and Nutritional Examination Survey (2007-2012) with the National Death Index. The analytic sample included adults ages 20 to 79 without missing data on age, sex, height, BMI, race/ethnicity, and smoking status. We defined COPD (GOLD 1, 2, and 3-4) and PRISm using FEV

resultsPrevalence of COPD and PRISm from 2007-2012 ranged from 13.1%-14.3% and 9.6%-10.2%, respectively. We found significant differences in prevalence by sex, age, smoking status, and race/ethnicity. Males had higher rates of COPD regardless of stage, while females had higher rates of PRISm. COPD prevalence increased with age, but not PRISm, which was highest among middle-aged individuals. Compared to current and never smokers, former smokers showed lower rates of PRISm but higher rates of GOLD 1. COPD prevalence was highest among non-Hispanic White individuals, and PRISm was notably higher among non-Hispanic Black individuals (range 31.4%-37.4%). We found associations between PRISm and all-cause mortality (hazard ratio [HR]: 2.3 95% CI: 1.9-2.9) and various cause-specific deaths (HR ranges: 2.0-5.3). We also found associations between GOLD 2 (HR: 2.1, 95% CI: 1.7-2.6) or higher (HR: 4.2, 95% CI: 2.7-6.5) and all-cause mortality. Cause-specific mortality risk varied within COPD stages but typically increased with higher GOLD stage.

conclusionsThe prevalence of COPD and PRISm remained stable from 2007-2012. Greater attention should be paid to the potential impacts of PRISm due to its higher prevalence in minority groups and its associations with mortality across various causes including cancer.

Indexed as

Nutrition SurveysPulmonary Disease, Chronic ObstructiveAdultAgedFemaleForced Expiratory VolumeHumansMaleMiddle AgedPrevalenceRisk FactorsSpirometryUnited StatesYoung AdultChronic obstructive pulmonary diseasePreserved ratio impaired spirometry

Identifiers

PMID38750492
PMCPMC11096119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.