Evidence map›Paper›PMID 38750460›Full record

ArticleBMC cardiovascular disorders2024

Role of myocardial strain imaging in diagnosing inducible myocardial ischemia with treadmill contrast-enhanced stress echocardiography.

Rami M Abazid, Nilkanth Patil, Maged Elrayes, Mark Chandy, Magdi Hassanin, Andrew Mathew, Sabe De, Rodrigo Bagur, Nikolaos Tzemos

Erratum issuedAbstract read
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In one paragraph

Article in BMC cardiovascular disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Rami M AbazidNorthern Ontario Medical School (NOSM) University, Department of Medicine, Sault Area Hospital, Sault Ste. Marie, Canada. ramiabazid@yahoo.com.
Nilkanth PatilDivision of Cardiology, Department of Medicine, London Health Sciences Centre, University Hospital, 339 Windermere Road, PO Box 5010, London, ON, N6A 5A5, Canada.
Maged ElrayesDivision of Cardiology, Department of Medicine, London Health Sciences Centre, University Hospital, 339 Windermere Road, PO Box 5010, London, ON, N6A 5A5, Canada.
Mark ChandyDivision of Cardiology, Department of Medicine, London Health Sciences Centre, University Hospital, 339 Windermere Road, PO Box 5010, London, ON, N6A 5A5, Canada.
Magdi HassaninNorthern Ontario Medical School (NOSM) University, Department of Medicine, Sault Area Hospital, Sault Ste. Marie, Canada.
Andrew MathewDivision of Cardiology, Department of Medicine, London Health Sciences Centre, University Hospital, 339 Windermere Road, PO Box 5010, London, ON, N6A 5A5, Canada.
Sabe DeDivision of Cardiology, Department of Medicine, London Health Sciences Centre, University Hospital, 339 Windermere Road, PO Box 5010, London, ON, N6A 5A5, Canada.
Rodrigo BagurDivision of Cardiology, Department of Medicine, London Health Sciences Centre, University Hospital, 339 Windermere Road, PO Box 5010, London, ON, N6A 5A5, Canada.
Nikolaos TzemosDivision of Cardiology, Department of Medicine, London Health Sciences Centre, University Hospital, 339 Windermere Road, PO Box 5010, London, ON, N6A 5A5, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of this study is to analyze the diagnostic value of global longitudinal strain (GLS) in detecting inducible myocardial ischemia in patients with chest pain undergoing treadmill contrast-enhanced stress echocardiography (SE).

methodsWe retrospectively enrolled all patients who underwent invasive coronary angiography after treadmill contrast-enhanced SE. Rest and peak-stress myocardial GLS, segmental LS, and LS of 4-chamber (CH), 2-CH, and 3-CH views were reported. Luminal stenosis of more than 70% or fractional flow reserve (FFR) of < 0.8 was considered significant.

resultsIn total 33 patients were included in the final analysis, among whom sixteen patients (48.4%) had significant coronary artery stenosis. Averaged GLS, 3-CH, and 4-CH LS were significantly lower in patients with critical coronary artery stenosis compared to those without significant stenosis (-17.1 ± 7.1 vs. -24.2 ± 7.2, p = 0.041), (-18.2 ± 8.9 vs. -24.6 ± 8.2, p = 0.045) and (-14.8 ± 6.2 vs. -22.8 ± 7.8, p = 0.009), respectively. Receiver operating characteristic (ROC) analysis of ischemic and non-ischemic segments demonstrated that a cut-off value of -20% of stress LS had 71% sensitivity and 60% specificity for ruling out inducible myocardial ischemia (Area under the curve was AUC = 0.72, P < 0.0001).

conclusionMyocardial LS measured with treadmill contrast-enhanced stress echocardiography demonstrates potential value in identifying patients with inducible myocardial ischemia.

Indexed as

Contrast MediaCoronary AngiographyCoronary StenosisEchocardiography, StressPredictive Value of TestsAgedFemaleFractional Flow Reserve, MyocardialHumansMaleMiddle AgedMyocardial ContractionMyocardial IschemiaReproducibility of ResultsRetrospective StudiesVentricular Function, LeftContrast MediaContrastMyocardial strainStress EchocardiographyTreadmill

Identifiers

PMID38750460
PMCPMC11097493

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.