Evidence map›Paper›PMID 38750358›Full record

ArticleNature2024

Dimerization and antidepressant recognition at noradrenaline transporter.

Heng Zhang, Yu-Ling Yin, Antao Dai, Tianwei Zhang, Chao Zhang, Canrong Wu, Wen Hu, Xinheng He, Benxun Pan, Sanshan Jin and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Uptake Patterns of Peripheral Ganglia onEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Mechanisms of transport and analgesic compounds recognition by glycine transporter 2.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Heng Zhang *State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Yu-Ling Yin *Lingang Laboratory, Shanghai, China.
Antao Dai *State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Tianwei ZhangLingang Laboratory, Shanghai, China.
Chao ZhangNational Center for Drug Screening, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Canrong WuState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Wen HuState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Xinheng HeState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Benxun PanLingang Laboratory, Shanghai, China.ORCID 0000-0001-7982-1706
Sanshan JinLingang Laboratory, Shanghai, China.
Qingning YuanState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
Ming-Wei WangResearch Center for Deepsea Bioresources, Sanya, China.ORCID 0000-0001-6550-9017
Dehua YangState Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. dhyang@simm.ac.cn.ORCID 0000-0003-3028-3243
H Eric XuState Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. eric.xu@simm.ac.cn.ORCID 0000-0002-6829-8144
Yi JiangLingang Laboratory, Shanghai, China. yjiang@lglab.ac.cn.ORCID 0000-0002-0723-1413

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The noradrenaline transporter has a pivotal role in regulating neurotransmitter balance and is crucial for normal physiology and neurobiology

Indexed as

Antidepressive AgentsCryoelectron MicroscopyNorepinephrineNorepinephrine Plasma Membrane Transport ProteinsProtein MultimerizationApoproteinsAspartic AcidBinding SitesCholesterolHumansModels, MolecularProtein BindingSubstrate SpecificityAntidepressive AgentsApoproteinsAspartic AcidCholesterolNorepinephrineNorepinephrine Plasma Membrane Transport ProteinsSLC6A2 protein, human

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.