Evidence map›Paper›PMID 38750297›Full record

ArticleCEN case reports2024

Tubulointerstitial nephritis with IgG4-positive plasma cell infiltration and tertiary lymphoid tissue in a patient with cryoglobulinemic vasculitis: a case report.

Yoshikuni Nagayama, Sakurako Yoshioka, Ayana Ichikura-Iida, Takashi Inoue, Koki Maeda, Masako Otani, Shigeki Iwasaki

Abstract readCase Reports
In one paragraph

Article in CEN case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yoshikuni NagayamaDepartment of Nephrology, Yokohama Municipal Citizen's Hospital, 1-1, Mitsuzawa Nisimachi, Kanagawa-ku, Yokohama, Kanagawa, 221-0855, Japan. ynaga1147@yahoo.co.jp.ORCID 0000-0002-3236-9078
Sakurako YoshiokaDepartment of Nephrology, Yokohama Municipal Citizen's Hospital, 1-1, Mitsuzawa Nisimachi, Kanagawa-ku, Yokohama, Kanagawa, 221-0855, Japan.
Ayana Ichikura-IidaDepartment of Nephrology, Yokohama Municipal Citizen's Hospital, 1-1, Mitsuzawa Nisimachi, Kanagawa-ku, Yokohama, Kanagawa, 221-0855, Japan.
Takashi InoueDepartment of Nephrology, Yokohama Municipal Citizen's Hospital, 1-1, Mitsuzawa Nisimachi, Kanagawa-ku, Yokohama, Kanagawa, 221-0855, Japan.
Koki MaedaDepartment of Diagnostic Pathology, Yokohama Municipal Citizen's Hospital, Yokohama, Japan.
Masako OtaniDepartment of Pathology, International University of Health and Welfare Mita Hospital, Tokyo, Japan.
Shigeki IwasakiDepartment of Nephrology, Yokohama Municipal Citizen's Hospital, 1-1, Mitsuzawa Nisimachi, Kanagawa-ku, Yokohama, Kanagawa, 221-0855, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tertiary lymphoid tissue (TLT) develops at sites of chronic immune stimulation, including infection, autoimmune disease, transplant rejection, and cancer. Recently, TLT has been focused on an indicator for poor renal prognosis in various kidney diseases. In cryoglobulinemic vasculitis (CV), specific glomerular and vascular lesions are seen; however, tubulointerstitial lesions are usually nonspecific. We herein report the case of a 74-year-old man with idiopathic CV with rare tubulointerstitial lesions, such as tubulointerstitial nephritis (TIN) with IgG4-positive plasma cell infiltration and TLT. To our knowledge, this is the first report identifying TLT in the kidney biopsy in a patient with CV. Glucocorticoid improved the renal outcome. The association between CV and TIN with TLT remains unknown.

Indexed as

CryoglobulinemiaImmunoglobulin GNephritis, InterstitialPlasma CellsVasculitisAgedBiopsyGlucocorticoidsHumansKidneyMaleTertiary Lymphoid StructuresGlucocorticoidsImmunoglobulin GCryoglobulinemic vasculitisImmunoglobulin G4Immunoglobulin G4-related kidney diseaseImmunoglobulin G4-related tubulointerstitial nephritisTertiary lymphoid tissue

Identifiers

PMID38750297
PMCPMC11608203

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.