Evidence map›Paper›PMID 38750255›Full record

ArticleSpinal cord2024

Does cardiometabolic risk profile differ among individuals with traumatic and non-traumatic spinal cord injury (SCI): the evidence from the multicenter SCI cohort in Switzerland (SwiSCI).

Peter Francis Raguindin, Oche Adam Itodo, Inge Eriks-Hoogland, Taulant Muka, Mirjam Brach, Gerold Stucki, Jivko Stoyanov, Marija Glisic

Abstract readMulticenter Study
In one paragraph

Article in Spinal cord, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Peter Francis RaguindinSwiss Paraplegic Research, Guido A. Zäch Strasse 1, 6207, Nottwil, Switzerland.ORCID 0000-0001-9716-4746
Oche Adam ItodoSwiss Paraplegic Research, Guido A. Zäch Strasse 1, 6207, Nottwil, Switzerland.ORCID 0000-0002-0702-1301
Inge Eriks-HooglandSwiss Paraplegic Research, Guido A. Zäch Strasse 1, 6207, Nottwil, Switzerland.ORCID 0000-0001-7388-6656
Taulant MukaInstitute of Social and Preventive Medicine, University of Bern, Mittelstrasse 43, 3012, Bern, Switzerland.
Mirjam BrachSwiss Paraplegic Research, Guido A. Zäch Strasse 1, 6207, Nottwil, Switzerland.
Gerold StuckiSwiss Paraplegic Research, Guido A. Zäch Strasse 1, 6207, Nottwil, Switzerland.
Jivko StoyanovSwiss Paraplegic Research, Guido A. Zäch Strasse 1, 6207, Nottwil, Switzerland.ORCID 0000-0001-6842-6284
Marija GlisicSwiss Paraplegic Research, Guido A. Zäch Strasse 1, 6207, Nottwil, Switzerland. marija.glisic@unibe.ch.ORCID 0000-0002-0108-2576

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designLongitudinal study.

objectiveTo explore whether individuals with traumatic spinal cord injury (TSCI) and non-traumatic SCI (NTSCI) experience different trajectories in changes of cardiometabolic disease (CMD) factors during initial rehabilitation stay.

settingMulticenter Swiss Spinal Cord Injury Cohort (SwiSCI) study.

methodsIndividuals without history of cardiovascular diseases were included. CMD factors and Framingham risk score (FRS) were compared between TSCI and NTSCI. Linear mixed models' analysis was employed to explore the trajectory in CMD factors changes over rehabilitation period and a multivariate linear regression analysis was used at discharge from inpatient rehabilitation to explore factors associated with CMD risk profile in TSCI and NTSCI. We performed age and sex-stratified analyses.

resultsWe analyzed 530 individuals with SCI (64% with TSCI and 36% NTSCI). The median age was 53 years (IQR:39-64) with 67.9% (n = 363) of the study cohort being male. The median rehabilitation duration was 4.4 months (IQR 2.4-6.4). At admission to rehabilitation, FRS (9.61 vs. 5.89) and prevalence of hypertension (33.16% vs. 13.62%), diabetes (13.68% vs. 4.06%), and obesity (79.05% vs. 66.67%) were higher in NTSCI as compared to TSCI, No difference was observed in cardiometabolic syndrome between the groups (around 40% in both groups). Overall, we observed longitudinal increases in total cholesterol, HDL-C and HDL/total cholesterol ratio, and a decrease in fasting glucose over the rehabilitation period. No differences in longitudinal changes in cardiovascular risk factors were observed between TSCI and NTSCI.

conclusionsThere was no deterioration in cardiometabolic risk factors over rehabilitation period, at discharge from initial rehabilitation stay. Both TSCI and NTSCI experienced high burden of cardiometabolic syndrome components with NTSCI experiencing more disadvantageous risk profile. The effectiveness of therapeutic and lifestyle/behavioral strategies to decrease burden of cardiometabolic disease and its components in early phase should be explored in future studies.

Indexed as

Cardiometabolic Risk FactorsSpinal Cord InjuriesAdultCardiovascular DiseasesCohort StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedSwitzerland

Identifiers

PMID38750255
PMCPMC11230898

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