Evidence map›Paper›PMID 38750247›Full record

ArticleScientific reports2024

Identification of Gα

Manae Tatsumi, Christian Cruz, Nozomi Kamakura, Riku Kuwabara, Gaku Nakamura, Tatsuya Ikuta, Ravinder Abrol, Asuka Inoue

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Manae TatsumiGraduate School of Pharmaceutical Sciences, Tohoku University, 6-3, Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
Christian CruzDepartment of Chemistry and Biochemistry, California State University, Northridge, CA, 91330, USA.
Nozomi KamakuraGraduate School of Pharmaceutical Sciences, Tohoku University, 6-3, Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
Riku KuwabaraGraduate School of Pharmaceutical Sciences, Tohoku University, 6-3, Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
Gaku NakamuraGraduate School of Pharmaceutical Sciences, Tohoku University, 6-3, Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
Tatsuya IkutaGraduate School of Pharmaceutical Sciences, Tohoku University, 6-3, Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
Ravinder AbrolDepartment of Chemistry and Biochemistry, California State University, Northridge, CA, 91330, USA.
Asuka InoueGraduate School of Pharmaceutical Sciences, Tohoku University, 6-3, Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan. iaska@tohoku.ac.jp.

Funding

Probing the Structural Basis of Innate G Protein Specificity in G Protein-Coupled Receptor SignalingSC2GM130480 · NIGMS · CALIFORNIA STATE UNIVERSITY NORTHRIDGE · PI ABROL, RAVINDER · 2020 to 2022
$435k
Japan Agency for Medical Research and Development JP22ama121038 and JP22zf0127007Japan Science and Technology Agency JPMJFR215T, JPMJMS2023 and 22714181Japan Society for the Promotion of Science JP22J10475Japan Society for the Promotion of Science P21H04791, JP21H05113, JPJSBP120213501 and JPJSBP120218801NIGMS NIH HHS SC2 GM130480NIH HHS SC2GM130480
6 · The paper itself

Abstract

G-protein-coupled receptors (GPCRs) transduce diverse signals into the cell by coupling to one or several Gα subtypes. Of the 16 Gα subtypes in human cells, Gα

Indexed as

GTP-Binding Protein alpha Subunits, G12-G13Molecular Dynamics SimulationReceptors, G-Protein-CoupledDesigner DrugsHEK293 CellsHumansProtein BindingDesigner DrugsGTP-Binding Protein alpha Subunits, G12-G13Receptors, G-Protein-Coupled

Identifiers

PMID38750247
PMCPMC11096383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.