Evidence map›Paper›PMID 38750194›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2024

Presurgical pulmonary function tests in the first few days of life in neonates with congenital heart disease, a pilot study.

Hayden Leeds, Ashok Muralidaran, Alicia J Johnson, Diane Schilling, Kseniya Parkhotyuk, Irving Shen, Cindy T McEvoy

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Hayden LeedsDepartment of Pediatrics, Oregon Health and Science University, Portland, OR, USA. leedsh@ohsu.edu.ORCID 0009-0002-4700-3092
Ashok MuralidaranDepartment of Surgery, Section of Pediatric and Congenital Heart Surgery, Oregon Health and Science University, Portland, OR, USA.
Alicia J JohnsonDepartment of Surgery, Oregon Health and Science University, Portland, OR, USA.
Diane SchillingDepartment of Pediatrics, Division of Neonatology, Oregon Health and Science University, Portland, OR, USA.
Kseniya ParkhotyukDepartment of Pediatrics, Division of Neonatology, Oregon Health and Science University, Portland, OR, USA.
Irving ShenDepartment of Surgery, Section of Pediatric and Congenital Heart Surgery, Oregon Health and Science University, Portland, OR, USA.
Cindy T McEvoyDepartment of Pediatrics, Division of Neonatology, Oregon Health and Science University, Portland, OR, USA.ORCID 0000-0001-8501-8813

Funding

Extending CPAP Therapy in Stable Preterm Infants to Increase Lung Growth and Function: A Randomized Controlled TrialR33HL147906 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI MCEVOY, CYNTHIA T, TEPPER, ROBERT S. · 2020 to 2023
$2.7M
Gerber Foundation 6276NHLBI NIH HHS R33 HL147906U.S. Department of Health & Human Services | NIH | National Heart, Lung, and Blood Institute (NHLBI) R33HL147906
6 · The paper itself

Abstract

objectiveTo compare early pulmonary function tests (PFTs) in neonates with critical congenital heart disease (CHD) compared to a historical reference group.

designInfants ≥ 37 weeks gestation with critical CHD were studied within the first few days of life, prior to cardiac surgery, and compared to data from a published reference group of healthy term neonates without CHD, studied at the same institution. Passive respiratory resistance (Rrs) and compliance (Crs) were measured with the single breath occlusion technique following specific acceptance criteria. The study was powered for a 30% difference in Rrs.

resultsPFTs in 24 infants with CHD were compared to 31 historical reference infants. There was no difference in the Rrs between the groups. The infants with CHD had a significantly decreased Crs (1.02 ± 0.26 mL/cmH2O/kg versus 1.32 ± 0.36; (p < 0.05; mean ± SD)).

conclusionsFurther prospective studies are required to quantify early PFTs in infants with CHD of different phenotypes.

Indexed as

Heart Defects, CongenitalRespiratory Function TestsAirway ResistanceCase-Control StudiesFemaleHumansInfant, NewbornLung ComplianceMalePilot ProjectsPreoperative CareProspective Studies

Identifiers

PMID38750194

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.