Evidence map›Paper›PMID 38750155›Full record

ArticleScientific reports2024

Chemical and biophysical characterization of novel potassium channel blocker 3-fluoro-5-methylpyridin-4-amine.

Yang Sun, Sofia Rodríguez-Rangel, Lauren L Zhang, Jorge E Sánchez-Rodríguez, Pedro Brugarolas

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Synthesis of KBioorganic & medicinal chemistry letters · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Yang Sun *Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.
Sofia Rodríguez-Rangel *Departamento de Física, Universidad de Guadalajara, Guadalajara, Jalisco, 44430, México.
Lauren L ZhangDepartment of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.
Jorge E Sánchez-RodríguezDepartamento de Física, Universidad de Guadalajara, Guadalajara, Jalisco, 44430, México. jorge.srodriguez@academicos.udg.mx.ORCID 0000-0001-8747-7239
Pedro BrugarolasDepartment of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA. pbrugarolas@mgh.harvard.edu.ORCID 0000-0002-7455-2743

Funding

Can [18F]3F4AP Detect Brain Demyelination? Evaluation of Novel PET Tracer in Nonhuman Primates and HumansR01NS114066 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI BRUGAROLAS, PEDRO · 2020 to 2024
$1.8M
CONAHCyT, Mexico 886951Harvard College Research Program 2023NINDS NIH HHS R01 NS114066NINDS NIH HHS R01NS114066PROSNI-UdeG, Mexico 2022
6 · The paper itself

Abstract

4-aminopyridine (4AP) is a potassium (K

Indexed as

Positron-Emission TomographyPotassium Channel Blockers4-AminopyridineAmifampridineHumans4-AminopyridineAmifampridinePotassium Channel Blockers

Identifiers

PMID38750155
PMCPMC11096398

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.