Evidence map›Paper›PMID 38750077›Full record

ArticleScientific reports2024

Mechanical behavior of full-thickness burn human skin is rate-independent.

Samara Gallagher, Kartik Josyula, Rahul, Uwe Kruger, Alex Gong, Agnes Song, Emily Eschelbach, David Crawford, Tam Pham, Robert Sweet and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Samara GallagherDepartment of Mechanical, Aerospace, and Nuclear Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA.
Kartik JosyulaCenter for Modeling, Simulation, and Imaging in Medicine, Rensselaer Polytechnic Institute, Troy, NY, USA.
RahulCenter for Modeling, Simulation, and Imaging in Medicine, Rensselaer Polytechnic Institute, Troy, NY, USA. rahul@rpi.edu.
Uwe KrugerCenter for Modeling, Simulation, and Imaging in Medicine, Rensselaer Polytechnic Institute, Troy, NY, USA.
Alex GongCenter for Research in Education and Simulation Technologies, University of Washington, Seattle, WA, USA.
Agnes SongCenter for Research in Education and Simulation Technologies, University of Washington, Seattle, WA, USA.
Emily EschelbachUW Medicine Regional Burn Center at Harborview Medical Center, University of Washington, Seattle, WA, USA.
David CrawfordUW Medicine Regional Burn Center at Harborview Medical Center, University of Washington, Seattle, WA, USA.
Tam PhamUW Medicine Regional Burn Center at Harborview Medical Center, University of Washington, Seattle, WA, USA.
Robert SweetCenter for Research in Education and Simulation Technologies, University of Washington, Seattle, WA, USA.
Conner ParseyU.S. Army Combat Capabilities Development Command - Soldier Center, Simulation and Training Technology Center, Orlando, FL, USA.
Jack NorfleetU.S. Army Combat Capabilities Development Command - Soldier Center, Simulation and Training Technology Center, Orlando, FL, USA.
Suvranu DeDepartment of Mechanical, Aerospace, and Nuclear Engineering, Rensselaer Polytechnic Institute, Troy, NY, USA.

Funding

U.S. Army Futures Command, Combat Capabilities Development Command Soldier Center STTC W911NF-17-2-0022U.S. Army Futures Command, Combat Capabilities Development Command Soldier Center STTC W912CG-20-2-0004
6 · The paper itself

Abstract

Skin tissue is recognized to exhibit rate-dependent mechanical behavior under various loading conditions. Here, we report that the full-thickness burn human skin exhibits rate-independent behavior under uniaxial tensile loading conditions. Mechanical properties, namely, ultimate tensile stress, ultimate tensile strain, and toughness, and parameters of Veronda-Westmann hyperelastic material law were assessed via uniaxial tensile tests. Univariate hypothesis testing yielded no significant difference (p > 0.01) in the distributions of these properties for skin samples loaded at three different rates of 0.3 mm/s, 2 mm/s, and 8 mm/s. Multivariate multiclass classification, employing a logistic regression model, failed to effectively discriminate samples loaded at the aforementioned rates, with a classification accuracy of only 40%. The median values for ultimate tensile stress, ultimate tensile strain, and toughness are computed as 1.73 MPa, 1.69, and 1.38 MPa, respectively. The findings of this study hold considerable significance for the refinement of burn care training protocols and treatment planning, shedding new light on the unique, rate-independent behavior of burn skin.

Indexed as

BurnsSkinStress, MechanicalTensile StrengthAdultBiomechanical PhenomenaElasticityFemaleHumansMaleMiddle AgedSkin Physiological Phenomena

Identifiers

PMID38750077
PMCPMC11096406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.