Evidence map›Paper›PMID 38749734›Full record

ArticleInternal medicine (Tokyo, Japan)2025

A Male Japanese Patient with Temple Syndrome Complicated by Type 2 Diabetes Mellitus.

Masanori Iwanishi, Tohru Yorifuji, Yukako Yamamoto, Jun Ito-Kobayashi, Akira Shimatsu, Shingo Kikugawa, Masayo Kagami

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Masanori IwanishiDepartment of Diabetes and Endocrinology, Omi Medical Center, Japan.
Tohru YorifujiSecond Department of Internal Medicine, Date Red Cross Hospital, Japan.
Yukako YamamotoDepartment of Diabetes and Endocrinology, Omi Medical Center, Japan.
Jun Ito-KobayashiDepartment of Diabetes and Endocrinology, Omi Medical Center, Japan.
Akira ShimatsuDepartment of Diabetes and Endocrinology, Omi Medical Center, Japan.
Shingo KikugawaDNA Chip Research, Japan.
Masayo KagamiDepartment of Molecular Endocrinology, National Research Institute for Child Health and Development, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein present the case of a 21-year-old male Japanese diabetic patient with Temple syndrome, caused by maternal uniparental disomy of chromosome 14. The patient was overweight and had type 2 diabetes, dyslipidemia, metabolic dysfunction-associated steatotic liver disease, and microalbuminuria. He had an increased fat mass in the truncal region and a decreased lean mass throughout the body. This may lead to insulin resistance due to the absence of delta-like homolog 1 (DLK1) and retrotransposon gag-like 1 (RTL1). The patient had experienced social withdrawal at home (hikikomori in Japanese), had poorly controlled type 2 diabetes, and was overweight despite receiving diet therapy and oral hypoglycemic agents.

Indexed as

Diabetes Mellitus, Type 2East Asian PeopleFaciesHumansImprinting DisordersInsulin ResistanceJapanMaleMuscle HypotoniaYoung Adultinsulin resistancematernal uniparental disomy of chromosome 14 (UPD(14)mat)Temple syndrometruncal obesitytype 2 diabetes

Identifiers

PMID38749734
PMCPMC11802230

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.