Evidence map›Paper›PMID 38749419›Full record

ArticleBiofabrication2024

Droplet bioprinting of acellular and cell-laden structures at high-resolutions.

Puskal Kunwar, Ujjwal Aryal, Arun Poudel, Daniel Fougnier, Zachary J Geffert, Rui Xie, Zhen Li, Pranav Soman

Abstract read
In one paragraph

Article in Biofabrication, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Effective and new technologies in kidney tissue engineering.Frontiers in bioengineering and biotechnology · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Puskal KunwarBiomedical, and Chemical Engineering Department, Syracuse University, Syracuse, NY 13210, United States of America.ORCID 0000-0002-5668-6414
Ujjwal AryalBiomedical, and Chemical Engineering Department, Syracuse University, Syracuse, NY 13210, United States of America.
Arun PoudelBiomedical, and Chemical Engineering Department, Syracuse University, Syracuse, NY 13210, United States of America.
Daniel FougnierBiomedical, and Chemical Engineering Department, Syracuse University, Syracuse, NY 13210, United States of America.
Zachary J GeffertBiomedical, and Chemical Engineering Department, Syracuse University, Syracuse, NY 13210, United States of America.
Rui XieBiomedical, and Chemical Engineering Department, Syracuse University, Syracuse, NY 13210, United States of America.
Zhen LiDepartment of Mechanical Engineering, Clemson University, Clemson, SC 29634, United States of America.
Pranav SomanBiomedical, and Chemical Engineering Department, Syracuse University, Syracuse, NY 13210, United States of America.ORCID 0000-0001-9456-0030

Funding

High-Throughput Single Cell MechanomicsR21GM141573 · NIGMS · SYRACUSE UNIVERSITY · PI SOMAN, PRANAV · 2021 to 2022
$430k
NIGMS NIH HHS R21 GM141573
6 · The paper itself

Abstract

Advances in digital light projection(DLP) based (bio) printers have made printing of intricate structures at high resolution possible using a wide range of photosensitive bioinks. A typical setup of a DLP bioprinter includes a vat or reservoir filled with liquid bioink, which presents challenges in terms of cost associated with bioink synthesis, high waste, and gravity-induced cell settling, contaminations, or variation in bioink viscosity during the printing process. Here, we report a vat-free, low-volume, waste-free droplet bioprinting method capable of rapidly printing 3D soft structures at high resolution using model bioinks and model cells. A multiphase many-body dissipative particle dynamics model was developed to simulate the dynamic process of droplet-based DLP printing and elucidate the roles of surface wettability and bioink viscosity. Process variables such as light intensity, photo-initiator concentration, and bioink formulations were optimized to print 3D soft structures (∼0.4-3 kPa) with a typical layer thickness of 50

Indexed as

BioprintingPrinting, Three-DimensionalAnimalsCell SurvivalHumansInkMiceTissue EngineeringTissue ScaffoldsViscosityWettabilitybioinkbioprintingDLPDropletlow-volumemodelvat-free

Identifiers

PMID38749419
PMCPMC12117511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.