Evidence map›Paper›PMID 38748992›Full record

ArticleInterdisciplinary cardiovascular and thoracic surgery2025

Effect of budesonide-formoterol powder inhalation on cough and lung function following thoracoscopic pulmonary surgery: a retrospective cohort study.

Jingyao Sun, Zhaoyao Hou, Tian Xia, Chang Liu, Qiangwen Huang, Li Wei

Abstract read
In one paragraph

Article in Interdisciplinary cardiovascular and thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jingyao SunDepartment of Thoracic Surgery, Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Zhengzhou, Henan, China.ORCID 0009-0008-9125-6541
Zhaoyao HouDepartment of Thoracic Surgery, Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Zhengzhou, Henan, China.ORCID 0000-0002-1781-9245
Tian XiaDepartment of Thoracic Surgery, Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Zhengzhou, Henan, China.
Chang LiuDepartment of Thoracic Surgery, Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Zhengzhou, Henan, China.ORCID 0009-0003-4898-2939
Qiangwen HuangDepartment of Thoracic Surgery, Henan University People's Hospital, Henan Provincial People's Hospital, Zhengzhou, Henan, China.ORCID 0009-0004-8863-440X
Li WeiDepartment of Thoracic Surgery, Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Zhengzhou, Henan, China.

Funding

Ministry of Science and Technology of Henan ProvinceScience and Technology Research Project of Henan Province 222102310511
6 · The paper itself

Abstract

objectivesTo explore whether portable budesonide-formoterol powder inhalation can ameliorate cough symptoms and improve pulmonary function recovery in patients who underwent thoracoscopic lung surgery.

methodsClinical data of patients who underwent thoracoscopic pulmonary resection at Henan Provincial People's Hospital between December 2022 and May 2023 were extracted. To evaluate the impact of continuous postoperative use of portable budesonide-formoterol powder inhalation, patients were divided into two groups: the control group and the case group. Next, we compared the Leicester cough score and pulmonary function indexes of the patients before surgery, 1 month and 6 months after the operation.

resultsA total of 188 cases were included, and the baseline demographic characteristics of both groups were well-balanced. The internal consistency of the Mandarin Chinese version of the Leicester Cough Questionnaire (LCQ-MC) scale, as indicated by Cronbach's α coefficients, was all greater than 0.8, and there was no significant difference in LCQ-MC scores between the two groups before the operation (Z = -1.173, P = 0.241). Postoperatively, the LCQ-MC score in the case group was significantly higher than that in the control group (18.66 vs 16.79, P < 0.01), with a notable statistically significant difference in the reduction of LCQ-MC scores between the two groups (1.32 vs 3.30, P < 0.01). Analysis of lung function revealed that patients in the case group exhibited significant improvements in FEV1/FVC, FVC, FEV1, PEF, MMEF75/25, MVV, DLCO and the RV/TLC indexes compared to the control group (P < 0.01).

conclusionsPortable budesonide-formoterol powder inhalation can alleviate cough symptoms and promote pulmonary function recovery in patients following thoracoscopic lung surgery.

Indexed as

Bronchodilator AgentsBudesonideBudesonide, Formoterol Fumarate Drug CombinationCoughFormoterol FumarateLungPneumonectomyThoracoscopyAdministration, InhalationAdultAgedFemaleHumansMaleMiddle AgedPowdersBronchodilator AgentsBudesonideBudesonide, Formoterol Fumarate Drug CombinationFormoterol FumaratePowdersbudesonide–formoterol fumarate drug combinationcoughlung functionthoracoscopic lung surgery

Identifiers

PMID38748992
PMCPMC12085221

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.