Evidence map›Paper›PMID 38748946›Full record

ArticleJornal brasileiro de nefrologia2024

Bone aluminum accumulation in the current era.

Rodrigo Bueno de Oliveira, Aluízio Barbosa Carvalho, Vanda Jorgetti

Abstract readEditorial
In one paragraph

Article in Jornal brasileiro de nefrologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Rodrigo Bueno de OliveiraUniversidade Estadual de Campinas (Unicamp), Faculdade de Ciências Médicas, Laboratório para o Estudo Mineral e Ósseo em Nefrologia (LEMON), Campinas, SP, Brazil.ORCID http://orcid.org/0000-0002-8273-6200
Aluízio Barbosa CarvalhoUniversidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Nefrologia, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-5907-7764
Vanda JorgettiUniversidade de São Paulo, Faculdade de Medicina, Departamento de Clínica Médica, Laboratório de Fisiopatologia Renal (LIM-16), São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0002-4824-8879

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last few years, evidence from the Brazilian Registry of Bone Biopsy (REBRABO) has pointed out a high incidence of aluminum (Al) accumulation in the bones of patients with CKD under dialysis. This surprising finding does not appear to be merely a passive metal accumulation, as prospective data from REBRABO suggest that the presence of Al in bone may be independently associated with major adverse cardiovascular events. This information contrasts with the perception of epidemiologic control of this condition around the world. In this opinion paper, we discussed why the diagnosis of Al accumulation in bone is not reported in other parts of the world. We also discuss a range of possibilities to understand why bone Al accumulation still occurs, not as a classical syndrome with systemic signs of intoxication, as occurred it has in the past.

Indexed as

AluminumBone and BonesBrazilHumansRenal DialysisRenal Insufficiency, ChronicAluminum

Identifiers

PMID38748946
PMCPMC11203949

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.