Evidence map›Paper›PMID 38748757›Full record

ArticleACS applied bio materials2024

Structure-Dependent Water Responsiveness of Protein Block Copolymers.

Jacob Kronenberg, Yeojin Jung, Jason Chen, Maria Jinu Kulapurathazhe, Dustin Britton, Seungri Kim, Xi Chen, Raymond S Tu, Jin Kim Montclare

Abstract read
In one paragraph

Article in ACS applied bio materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jacob KronenbergDepartment of Chemical and Biomolecular Engineering, New York University Tandon School of Engineering, Brooklyn, New York 11201, United States.
Yeojin JungAdvanced Science Research Center (ASRC) at the Graduate Center, City University of New York, New York, New York 10031, United States.
Jason ChenDepartment of Chemical and Biomolecular Engineering, New York University Tandon School of Engineering, Brooklyn, New York 11201, United States.
Maria Jinu KulapurathazheDepartment of Chemical and Biomolecular Engineering, New York University Tandon School of Engineering, Brooklyn, New York 11201, United States.
Dustin BrittonDepartment of Chemical and Biomolecular Engineering, New York University Tandon School of Engineering, Brooklyn, New York 11201, United States.
Seungri KimAdvanced Science Research Center (ASRC) at the Graduate Center, City University of New York, New York, New York 10031, United States.
Xi ChenAdvanced Science Research Center (ASRC) at the Graduate Center, City University of New York, New York, New York 10031, United States.ORCID 0000-0002-2985-358X
Raymond S TuDepartment of Chemical Engineering, City College of New York, New York, New York 10031, United States.ORCID 0000-0002-6192-7665
Jin Kim MontclareDepartment of Chemical and Biomolecular Engineering, New York University Tandon School of Engineering, Brooklyn, New York 11201, United States.ORCID 0000-0001-6857-3591

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biological water-responsive (WR) materials are abundant in nature, and they are used as mechanical actuators for seed dispersal by many plants such as wheat awns and pinecones. WR biomaterials are of interest for applications as high-energy actuators, which can be useful in soft robotics or for capturing energy from natural water evaporation. Recent work on WR silk proteins has shown that β-sheet nanocrystalline domains with high stiffness correlate with the high WR actuation energy density, but the fundamental mechanisms to drive water responsiveness in proteins remain poorly understood. Here, we design, synthesize, and study protein block copolymers consisting of two α-helical domains derived from cartilage oligomeric matrix protein coiled-coil (C) flanking an elastin-like peptide domain (E), namely, CEC. We use these protein materials to create WR actuators with energy densities that outperform mammalian muscle. To elucidate the effect of structure on WR actuation, CEC was compared to a variant, CEC

Indexed as

Biocompatible MaterialsMaterials TestingWaterCartilage Oligomeric Matrix ProteinElastinParticle SizePolymersBiocompatible MaterialsCartilage Oligomeric Matrix ProteinElastinPolymersWaterbiomaterialsblock copolymersprotein engineeringprotein filmswater-responsive materials

Identifiers

PMID38748757
PMCPMC11190970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.