A new three-dimensional (3D) molecularly imprinted polymer fluoroprobe based on green-red dual-emission signals of carbon quantum dots and self-polymerization of dopamine (CDs@PDA-MIPs) for sensitive detection of nifedipine.

Hao Liu, Xuyuan Sun, Zhengyuan Dai, Ying Wang, Li Li, Jie Fan, Yaping Ding

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Article in Mikrochimica acta, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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7 authors.

Hao LiuDepartment of Chemistry, College of Sciences, Shanghai University, Shanghai, 200444, People's Republic of China.

Xuyuan SunDepartment of Chemistry, College of Sciences, Shanghai University, Shanghai, 200444, People's Republic of China.

Zhengyuan DaiDepartment of Chemistry, College of Sciences, Shanghai University, Shanghai, 200444, People's Republic of China.

Ying WangDepartment of Chemistry, College of Sciences, Shanghai University, Shanghai, 200444, People's Republic of China.

Li LiDepartment of Chemistry, College of Sciences, Shanghai University, Shanghai, 200444, People's Republic of China. lilidu@shu.edu.cn.

Jie FanDepartment of Urology, School of Medicine, Shanghai First People's Hospital, Shanghai Jiaotong University, Shanghai, 200080, People's Republic of China. jief67@sina.com.

Yaping DingDepartment of Chemistry, College of Sciences, Shanghai University, Shanghai, 200444, People's Republic of China. wdingyp@sina.com.ORCID http://orcid.org/0000-0002-4275-8093

Funding

National Natural Science Foundation of China No. 22274096

6 · The paper itself

Abstract

Nifedipine (NIF), as one of the dihydropyridine calcium channel blockers, is widely used in the treatment of hypertension. However, misuse or ingestion of NIF can result in serious health issues such as myocardial infarction, arrhythmia, stroke, and even death. It is essential to design a reliable and sensitive detection method to monitor NIF. In this work, an innovative molecularly imprinted polymer dual-emission fluorescent sensor (CDs@PDA-MIPs) strategy was successfully designed for sensitive detection of NIF. The fluorescent intensity of the probe decreased with increasing NIF concentration, showing a satisfactory linear relationship within the range 1.0 × 10

Indexed as

CarbonDopamineFluorescent DyesLimit of DetectionMolecularly Imprinted PolymersNifedipineQuantum DotsSpectrometry, FluorescenceHumansMolecular ImprintingPolymerizationTabletsCarbonDopamineFluorescent DyesMolecularly Imprinted PolymersNifedipineTabletsCarbon quantum dotsDual-emissionFluorescent sensorMolecularly imprinted polymerNifedipine

Identifiers

PMID38748375

DOI10.1007/s00604-024-06407-z

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