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ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2024

Choroidal arterial abnormality in central serous chorioretinopathy.

Raimo Tuuminen, Sohee Jeon

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Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Raimo TuuminenHelsinki Retina Research Group, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Sohee JeonKeye Eye Center, 326 Teheran-Ro, Gangnam-Gu, Seoul, Republic of Korea. soheeeee@gmail.com.ORCID http://orcid.org/0000-0002-1291-0963

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the choroidal arterial abnormality in central serous chorioretinopathy (CSC).

methodsFifty-two eyes from 52 patients with CSC were retrospectively evaluated. Arterial and venous ultrawide-field indocyanine green angiography were merged after color and transparency adjustments to compare the choroidal arterial and venous vasculature. Specifically, we evaluated whether the choroidal arteries directly fill the pachyvessel without interconnection of choriocapillaris (arterial pachyvessel; aPV). Then, the clinical characteristics of patients with and without arterial pachyvessel were compared.

resultsPachyvessel under subretinal fluid was detected in 47 of 52 eyes (90.4%). An arterial pachyvessel was detected in eight of 52 eyes (15.4%). Of those eight eyes with arterial pachyvessel, seven (87.5%) showed sustained staining through the venous phase, suggesting they are arteriovenous shunt, while one eye (12.5%) showed diminished fluorescence in the venous phase, suggesting this pachyvessel was purely an artery. Patients with arterial pachyvessel experienced more CSC recurrences (non-aPV group: 2.09 ± 1.44 times vs. aPV group: 3.25 ± 1.28 times; p = 0.039) and pachychoroid neovasculopathy (PNV) development (non-aPV group: 2.3% vs. aPV group: 37.5%, p = 0.009).

conclusionThe presence of arterial pachyvessel in eyes with CSC may represent choroidal circulatory imbalance and focal shear stress to Bruch's membrane, leading to a chronic nature and PNV development.

Indexed as

Central Serous ChorioretinopathyChoroidFluorescein AngiographyFundus OculiTomography, Optical CoherenceVisual AcuityAdultColoring AgentsFemaleFollow-Up StudiesHumansIndocyanine GreenMaleMiddle AgedRetrospective StudiesColoring AgentsIndocyanine GreenArteriovenous shuntCentral serous chorioretinopathyPachychoroid neovasculopathyPachychoroid spectrum diseaseUltrawide-field indocyanine green angiography

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.