ArticleClinical research in cardiology : official journal of the German Cardiac Society2024
Myocardial work in chronic kidney disease: insights from the CPH-CKD ECHO Study.
Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Cardiorenal Syndrome and Autonomic Overactivity.Biomedicines · 2025Review
- Noninvasive Left Ventricular Pressure-Strain Loop for Assessment of Myocardial Work in Hemodialysis in Patients With Chronic Kidney Disease.Echocardiography (Mount Kisco, N.Y.) · 2025Article
- Risk factors for mechanical complications in very elderly patients with acute myocardial infarction.Frontiers in medicine · 2025Article
- The Spectrum of Echocardiographic Findings Across Stages I-V of Chronic Kidney Disease.Cureus · 2024Article
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Authors and funding
12 authors.
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Abstract
backgroundMyocardial work is a novel echocardiographic measure that offers detailed insights into cardiac mechanics. We sought to characterize cardiac function by myocardial work in patients with chronic kidney disease (CKD).
methodsWe prospectively enrolled 757 patients with non-dialysis-dependent CKD and 174 age- and sex-matched controls. Echocardiographic pressure-strain loop analysis was performed to acquire the global work index (GWI). Linear regressions were performed to investigate the association between estimated glomerular filtration rate (eGFR) and urine albumin-creatinine ratio (UACR) to GWI.
resultsPatients with CKD had a mean age of 57 years, 61% were men, and median eGFR was 42 mL/min/1.73 m
conclusionPatients with CKD and left ventricular hypertrophy exhibited lower myocardial work compared to matched controls. Furthermore, decreasing eGFR was associated with decreasing myocardial work only in patients without diabetes. No association to UACR was observed.
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