Evidence map›Paper›PMID 38747753›Full record

ReviewArquivos brasileiros de oftalmologia2024

Cutting-edge issues in sympathetic ophthalmia approach and six case reports: a T cell-mediated autoimmune response.

Fernando Henrique Flores Teixeira, Thiago Sande Miguel, Danielle Marcello Soares, Juliana Rocha, Ana Luiza Biancardi, Francisco Assis de Andrade, André Luiz Land Curi

Abstract readCase ReportsReview
In one paragraph

Review in Arquivos brasileiros de oftalmologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fernando Henrique Flores TeixeiraLaboratory of Infectious Diseases in Ophthalmology, Instituto Nacional Evandro Chagas, Rio de Janeiro, RJ, Brazil.ORCID 0000-0002-7429-3294
Thiago Sande MiguelOphthalmology Department, Universidade Federal Fluminense, Rio de Janeiro, RJ, Brazil.
Danielle Marcello SoaresOphthalmology Department, Centro de Estudos e Pesquisas Oculistas Associados, Rio de Janeiro, RJ, Brazil.
Juliana RochaOphthalmology Department, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Ana Luiza BiancardiLaboratory of Infectious Diseases in Ophthalmology, Instituto Nacional Evandro Chagas, Rio de Janeiro, RJ, Brazil.ORCID 0000-0002-0169-7001
Francisco Assis de AndradeDiscipline of Uveitis and Autoimmune Diseases, Centro de Estudos e Pesquisas Oculistas Associados, Rio de Janeiro, RJ, Brazil.ORCID 0000-0003-3248-8605
André Luiz Land CuriLaboratory of Infectious Diseases in Ophthalmology, Instituto Nacional Evandro Chagas, Rio de Janeiro, RJ, Brazil.ORCID 0000-0002-2764-4047

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sympathetic ophthalmia is a rare and potentially devastating bilateral diffuse granulomatous panuveitis. It is caused by surgical or non-surgical eye injuries and is an uncommon and serious complication of trauma. It is diagnosed clinically and supported by imaging examinations such as ocular ultrasonography and optical coherence tomography. Its treatment consists of immunosuppressive therapy with steroids and sometimes steroid-sparing drugs, such as cyclosporine, azathioprine, cyclophosphamide, and mycophenolate mofetil. Fast and effective management with systemic immunosuppressive agents allows for disease control and achievement of good visual acuity in the sympathizing eye. By contrast, enucleation should be considered only in situations where the injured eye has no light perception or in the presence of severe trauma. In addition to a bibliographic review of this topic, we report six cases involving different immunosuppressive and surgical treatment modalities.

Indexed as

Immunosuppressive AgentsOphthalmia, SympatheticAdultFemaleHumansMaleMiddle AgedT-LymphocytesTomography, Optical CoherenceVisual AcuityImmunosuppressive Agents

Identifiers

PMID38747753
PMCPMC11619712

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.