Evidence map›Paper›PMID 38747717›Full record

ArticleeLife2024

Claudia D Consalvo, Adedeji M Aderounmu, Helen M Donelick, P Joseph Aruscavage, Debra M Eckert, Peter S Shen, Brenda L Bass

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Viral infection drives cell-intrinsic re-localization of thebioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Intraspecific variation in the duration of epigenetic inheritance.bioRxiv : the preprint server for biology · 2025
    Article
  10. Biochemical and structural basis of Dicer helicase function unveiled by resurrecting ancient proteins.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  12. Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  13. bioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

  • Update of
    2024
5 · Who and what money

Authors and funding

7 authors.

Claudia D ConsalvoDepartment of Biochemistry, University of Utah, Salt Lake City, United States.ORCID https://orcid.org/0000-0003-2038-4315
Adedeji M Aderounmu *Department of Biochemistry, University of Utah, Salt Lake City, United States.
Helen M Donelick *Department of Biochemistry, University of Utah, Salt Lake City, United States.
P Joseph AruscavageDepartment of Biochemistry, University of Utah, Salt Lake City, United States.
Debra M EckertDepartment of Biochemistry, University of Utah, Salt Lake City, United States.
Peter S ShenDepartment of Biochemistry, University of Utah, Salt Lake City, United States.ORCID https://orcid.org/0000-0002-6256-6910
Brenda L BassDepartment of Biochemistry, University of Utah, Salt Lake City, United States.ORCID https://orcid.org/0000-0003-1728-2254

Funding

Pacific Northwest Center for Cryo-EM - Screening supplementU24GM129547 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI EVANS, JAMES E, GOUAUX, JAMES E · 2018 to 2023
$54.8M
NCCAT: National Center for CryoEM Access and Training- Supplement for Windows 10 and FFIU24GM129539 · NIGMS · NEW YORK STRUCTURAL BIOLOGY CENTER · PI DE MARCO, ALEX, KIEFT, JEFFREY S · 2018 to 2023
$53.9M
Training Program in Microbial PathogenesisT32AI055434 · NIAID · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI MULVEY, MATTHEW A, PLANELLES, VICENTE · 2004 to 2025
$6.0M
Unlocking evolutionarily latent immune functions for treating diseaseR01CA260414 · NCI · UNIVERSITY OF UTAH · PI BASS, BRENDA L., ELDE, NELS C. · 2020 to 2024
$5.8M
Elucidating roles and mechanisms of double-stranded RNA-mediated pathwaysR35GM141262 · NIGMS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Brenda L. Bass · 2021 to 2026
$3.7M
Visualizing the Mechanisms of Protein Quality ControlR35GM133772 · NIGMS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Peter Shen · 2019 to 2026
$3.4M
Amnis ImageStreamX MarkII Imaging Flow CytometerS10OD026959 · OD · UNIVERSITY OF UTAH · PI MARVIN, JAMES E · 2020 to 2020
$517k
NCI NIH HHS R01 CA260414NCI NIH HHS R01CA260414NIAID NIH HHS T32 AI055434NIGMS NIH HHS R35 GM133772NIGMS NIH HHS R35GM133772NIGMS NIH HHS R35 GM141262NIGMS NIH HHS R35GM141262NIGMS NIH HHS U24 GM129539NIGMS NIH HHS U24 GM129547NIH HHS S10 OD026959NIH HHS T32AI055434
6 · The paper itself

Abstract

Invertebrates use the endoribonuclease Dicer to cleave viral dsRNA during antiviral defense, while vertebrates use RIG-I-like Receptors (RLRs), which bind viral dsRNA to trigger an interferon response. While some invertebrate Dicers act alone during antiviral defense,

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsRibonuclease IIIRNA, Double-StrandedAdenosine TriphosphateAnimalsCryoelectron MicroscopyDEAD Box Protein 58DEAD-box RNA HelicasesProtein BindingRNA-Binding ProteinsRNA HelicasesAdenosine TriphosphateCaenorhabditis elegans ProteinsDEAD Box Protein 58DEAD-box RNA HelicasesRibonuclease IIIRNA-Binding ProteinsRNA, Double-StrandedRNA HelicasesantiviralautoinhibitionbiochemistryC. eleganschemical biologydsRNAinnate immunitymolecular biophysicsRNAistructural biologytranslocation

Identifiers

PMID38747717
PMCPMC11095941

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.