Evidence map›Paper›PMID 38747597›Full record

ArticlemSystems2024

Tuning interdomain conjugation to enable

Kevin R Stindt, Megan N McClean

Abstract read
In one paragraph

Article in mSystems, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Kevin R StindtDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-6028-3773
Megan N McCleanDepartment of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-1141-4802

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6M
Elucidating the network design principles of biological signal processingR35GM128873 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Megan N McClean · 2018 to 2026
$4.0M
Under-oil open microfluidic system (UOMS) for studying systemic fungal infectionR01AI154940 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI BEEBE, DAVID J, MCCLEAN, MEGAN N · 2021 to 2025
$3.8M
Predoctoral Training in Molecular BiophysicsT32GM130550 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI SENES, ALESSANDRO · 2019 to 2023
$1.5M
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI154940HHS | NIH | National Institute of General Medical Sciences (NIGMS) R35GM128873Molecular Biophysics Training Grant T32GM130550NCI NIH HHS P30 CA014520NIAID NIH HHS R01 AI154940NIGMS NIH HHS R35 GM128873NIGMS NIH HHS T32 GM130550University of Wisconsin Carbone Cancer Center (UWCCC) P30CA014520Wisconsin Alumni Research Foundation (WARF) 135AAI9593
6 · The paper itself

Abstract

The ability to modify and control natural and engineered microbiomes is essential for biotechnology and biomedicine. Fungi are critical members of most microbiomes, yet technology for modifying the fungal members of a microbiome has lagged far behind that for bacteria. Interdomain conjugation (IDC) is a promising approach, as DNA transfer from bacterial cells to yeast enables

Indexed as

Escherichia coliSaccharomyces cerevisiaeConjugation, GeneticconjugationCRISPRcrossfeedingexpansion assayfungihorizontal gene transfermicrobiomemycobiomepopulation modelingsynthetic consortia

Identifiers

PMID38747597
PMCPMC11326116

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.