Evidence map›Paper›PMID 38747593›Full record

ArticlemBio2024

mRNA cap-binding protein eIF4E1 is a novel regulator of

Michael J Holmes, Matheus S Bastos, Vishakha Dey, Vanessa Severo, Ronald C Wek, William J Sullivan

Abstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Structural basis for emetine inhibition of ribosome translocation inbioRxiv : the preprint server for biology · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. SPARK regulates AGC kinases central to thebioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Michael J HolmesDepartment of Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID 0000-0002-4562-287X
Matheus S BastosDepartment of Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Vishakha DeyDepartment of Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Vanessa SeveroDepartment of Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Ronald C WekDepartment of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
William J SullivanDepartment of Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID 0000-0003-1823-8642

Funding

Tumor Microenvironment and Metastasis ProgramP30CA082709 · NCI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI David W Clapp · 1999 to 2026
$59.3M
Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Translation initiation factors driving persistence of Toxoplasma gondii bradyzoites in neuronsR01AI172752 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI William J Sullivan, RONALD C WEK · 2023 to 2026
$2.3M
Regulation of cyst formation in the AIDS opportunistic pathogen ToxoplasmaR21AI167662 · NIAID · INDIANA UNIVERSITY INDIANAPOLIS · PI SULLIVAN, WILLIAM J, WEK, RONALD C · 2022 to 2023
$421k
American Heart Association (AHA) 20POST35150019HHS | National Institutes of Health (NIH) AI167662HHS | National Institutes of Health (NIH) AI172752NCATS NIH HHS UL1 TR002529NCI NIH HHS P30 CA082709NIAID NIH HHS R01 AI172752NIAID NIH HHS R21 AI167662
6 · The paper itself

Abstract

The protozoan parasite IMPORTANCE:

Indexed as

Eukaryotic Initiation Factor-4EProtozoan ProteinsRNA, MessengerToxoplasmaAnimalsEukaryotic Initiation Factor-4FHumansMiceProtein BiosynthesisToxoplasmosisEukaryotic Initiation Factor-4EEukaryotic Initiation Factor-4FProtozoan ProteinsRNA, Messengerbradyzoitegene expressionparasiteToxoplasmatranslation

Identifiers

PMID38747593
PMCPMC11237481

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.