Evidence map›Paper›PMID 38747577›Full record

ArticleeLife2024

Overcoming the nutritional immunity by engineering iron-scavenging bacteria for cancer therapy.

Sin-Wei Huang, See-Khai Lim, Yao-An Yu, Yi-Chung Pan, Wan-Ju Lien, Chung-Yuan Mou, Che-Ming Jack Hu, Kurt Yun Mou

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sin-Wei HuangInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.ORCID https://orcid.org/0009-0004-1593-6511
See-Khai LimInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Yao-An YuInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Yi-Chung PanInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Wan-Ju LienInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
Chung-Yuan MouDepartment of Chemistry, National Taiwan University, Taipei, Taiwan.
Che-Ming Jack HuInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.ORCID https://orcid.org/0000-0002-0988-7029
Kurt Yun MouInstitute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.ORCID https://orcid.org/0000-0001-5423-9031

Funding

Academia Sinica AS-CDA-108-L07National Science and Technology Council 110-2113-M-001-064-MY3
6 · The paper itself

Abstract

Certain bacteria demonstrate the ability to target and colonize the tumor microenvironment, a characteristic that positions them as innovative carriers for delivering various therapeutic agents in cancer therapy. Nevertheless, our understanding of how bacteria adapt their physiological condition to the tumor microenvironment remains elusive. In this work, we employed liquid chromatography-tandem mass spectrometry to examine the proteome of

Indexed as

Escherichia coliIronLipocalin-2AnimalsCell Line, TumorEnterobactinMiceNeoplasmsTumor MicroenvironmentEnterobactinIronLipocalin-2bacterial therapycancer biologyE. coliiron deficiencynutritional immunity

Identifiers

PMID38747577
PMCPMC11095936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.