Evidence map›Paper›PMID 38747471›Full record

ArticleThe Journal of clinical endocrinology and metabolism2025

Associations of Vegetable and Potato Intakes With Markers of Type 2 Diabetes Risk in the AusDiab Cohort.

Pratik Pokharel, Lauren C Blekkenhorst, Catherine P Bondonno, Kevin Murray, Simone Radavelli-Bagatini, Dianna J Magliano, Robin M Daly, Jonathan E Shaw, Joshua R Lewis, Jonathan M Hodgson and 1 more

Abstract read
In one paragraph

Article in The Journal of clinical endocrinology and metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Pratik PokharelNutrition and Health Innovation Research Institute, School of Medical and Health Sciences, Edith Cowan University, Perth, Western Australia 6000, Australia.ORCID 0000-0001-5815-5927
Lauren C BlekkenhorstNutrition and Health Innovation Research Institute, School of Medical and Health Sciences, Edith Cowan University, Perth, Western Australia 6000, Australia.
Catherine P BondonnoNutrition and Health Innovation Research Institute, School of Medical and Health Sciences, Edith Cowan University, Perth, Western Australia 6000, Australia.
Kevin MurraySchool of Population and Global Health, University of Western Australia, Perth, Western Australia 6009, Australia.ORCID 0000-0002-8856-6046
Simone Radavelli-BagatiniNutrition and Health Innovation Research Institute, School of Medical and Health Sciences, Edith Cowan University, Perth, Western Australia 6000, Australia.
Dianna J MaglianoDepartment of Diabetes and Population Health, Baker Heart and Diabetes Institute (HDI), Melbourne, Victoria 3004, Australia.
Robin M DalyInstitute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, Victoria 3220, Australia.
Jonathan E ShawDepartment of Diabetes and Population Health, Baker Heart and Diabetes Institute (HDI), Melbourne, Victoria 3004, Australia.
Joshua R LewisNutrition and Health Innovation Research Institute, School of Medical and Health Sciences, Edith Cowan University, Perth, Western Australia 6000, Australia.
Jonathan M HodgsonNutrition and Health Innovation Research Institute, School of Medical and Health Sciences, Edith Cowan University, Perth, Western Australia 6000, Australia.
Nicola P BondonnoNutrition and Health Innovation Research Institute, School of Medical and Health Sciences, Edith Cowan University, Perth, Western Australia 6000, Australia.ORCID 0000-0001-5905-444X

Funding

National Health and Medical Research Council Early Career Fellowship APP1159914National Heart Foundation of Australia 102498Royal Perth Hospital Research Foundation "Lawrie Beilin" Career Advancement Fellowship CAF 127/2020
6 · The paper itself

Abstract

contextThe associations of vegetable and potato intakes with type 2 diabetes (T2D) appear to be nuanced, depending on vegetable types and preparation method, respectively.

objectiveWe investigated the associations of total vegetable, vegetable subgroup, and potato intakes with (1) markers of T2D at baseline and (2) incident T2D cumulative over a 12-year follow-up period in Australian adults.

methodsUsing data from the Australian Diabetes, Obesity and Lifestyle Study, intakes of vegetables and potatoes were assessed via a food frequency questionnaire at baseline. Associations between vegetable intake and (1) fasting plasma glucose (FPG), 2-hour postload plasma glucose (PLG), updated homeostasis model assessment of β-cell function (HOMA2-%β), HOMA2 of insulin sensitivity (HOMA2-%S), and fasting insulin levels at baseline; and (2) cumulative incident T2D at the end of 12-year follow-up were examined using generalized linear and Cox proportional hazards models, respectively.

resultsIn total, 8009 participants were included having median age of 52 years, and vegetable intake of 132 g/day. Higher intake of total vegetable, green leafy, yellow/orange/red, and moderate intakes of cruciferous vegetables was associated with lower PLG. Additionally, higher green leafy vegetable intake was associated with lower HOMA2-%β and serum insulin. Conversely, higher potato fries/chips intakes were associated with higher FPG, HOMA2-%β, serum insulin, and lower HOMA2-%S. Participants with moderate cruciferous vegetables intake had a 25% lower risk of T2D at the end of 12 years of follow-up.

conclusionA higher intake of vegetables, particularly green leafy vegetables, may improve while consuming potato fries/chips, but not potatoes prepared in a healthy way, may worsen glucose tolerance and insulin sensitivity. Our findings suggest a nuanced relationship between vegetable subgroups and their impact on glucose tolerance.

Indexed as

BiomarkersDiabetes Mellitus, Type 2DietSolanum tuberosumVegetablesAdultAgedAustraliaBlood GlucoseCohort StudiesFemaleFollow-Up StudiesHumansIncidenceInsulinInsulin ResistanceBiomarkersBlood GlucoseInsulinBrassica vegetablesdiabetes markersgreen vegetablesleafy vegetablenutrition epidemiologytype 2 diabetes mellitus

Identifiers

PMID38747471
PMCPMC11913086

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.