Evidence map›Paper›PMID 38747192›Full record

ArticleJournal of veterinary internal medicine

Viscoelastic coagulation monitoring parameters in cats with acute arterial thromboembolism.

Amanda J Johnson, Elizabeth A Rozanski, Armelle M de Laforcade, Claudia Davila, John E Rush, Julien Guillaumin

Abstract readMulticenter Study
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
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  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Amanda J JohnsonFoster Hospital for Small Animals at Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA.
Elizabeth A RozanskiFoster Hospital for Small Animals at Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA.ORCID https://orcid.org/0000-0003-3233-8930
Armelle M de LaforcadeFoster Hospital for Small Animals at Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA.
Claudia DavilaFoster Hospital for Small Animals at Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA.
John E RushFoster Hospital for Small Animals at Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA.ORCID https://orcid.org/0000-0002-8277-8996
Julien GuillauminDepartment of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA.ORCID https://orcid.org/0000-0001-8622-4387

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypercoagulability has been documented in cats with cardiac disease. However, hemostatic parameters, including viscoelastic coagulation monitoring (VCM) have not been reported in cats with arterial thromboembolism (ATE). HYPOTHESIS/

objectivesCompare VCM parameters in cats with acute cardiogenic ATE and in control cats. ANIMALS: Sixteen cats with ATE and 30 control cats.

methodsMulticenter university-based prospective study. Cardiogenic ATE was diagnosed based on physical examination and by ultrasonographically-diagnosed left atrial enlargement. Viscoelastic coagulation monitor analysis, CBC, serum biochemistry profile and coagulation profile were performed at admission in cats with ATE. Analysis from healthy control cats was performed using blood collected by direct venipuncture. Our objective was comparison of VCM parameters clot time (CT), clot formation time (CFT), alpha angle (Angle), maximum clot formation (MCF), amplitude at 10 and 20 minutes (A10 and A20, respectively) and clot lysis index at 30 and 45 minutes (LI30 and LI45, respectively) between ATE and control cats.

resultsCats with ATE had a decreased angle compared to control cats, with a median (range) of 43° (30-48°) compared to 47° (14-59°; P = .01). The parameters A10, A20 and MCF were decreased in ATE cats compared to control cats with a median (range) of 19 units (8-32) compared to 22 units (6-38), 24.5 units (11-40) compared to 29 units (10-47) and 29.5 units (13-44) compared to 33.5 units (14-53), respectively (P = .01, .01 and .01, respectively). The parameters CT, CFT, LI30 and LI45 were similar between groups (P = .22, .09, .62 and .34, respectively). CONCLUSIONS AND CLINICAL IMPORTANCE: Cats with cardiogenic ATE cats have VCM parameters consistent with hypocoagulability compared with healthy cats.

Indexed as

Cat DiseasesThromboembolismAnimalsBlood CoagulationBlood Coagulation TestsCase-Control StudiesCatsFemaleMaleProspective Studiesfelinesaddle thrombusthromboelastogramthromboelastometrythrombosisviscoelastic

Identifiers

PMID38747192
PMCPMC11256171

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.