Evidence map›Paper›PMID 38747144›Full record

SynthesisCirculation. Cardiovascular quality and outcomes2024

Risks of Restrictive Versus Liberal Red Blood Cell Transfusion Strategies in Patients With Cardiovascular Disease: An Updated Meta-Analysis.

Willard N Applefeld, Verity J Ford, Irene Cortes-Puch, Jeffrey Wang, Junfeng Sun, Tracy C Shields, Robert L Danner, Peter Q Eichacker, Michael A Solomon, Harvey G Klein and 1 more

Abstract readMeta-AnalysisLetter
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Circulation. Cardiovascular quality and outcomes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Restrictive versus liberal transfusion thresholds: lights and shadows.Blood transfusion = Trasfusione del sangue · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Willard N Applefeld *Division of Cardiology, Duke University Medical Center, Durham, NC (W.N.A.).
Verity J Ford *Critical Care Medicine Department, Clinical Center (V.J.F., J.S., R.L.D., P.Q.E., M.A.S., C.N.), National Institutes of Health, Bethesda, MD.ORCID 0000-0002-1364-8522
Irene Cortes-PuchDivision of Pulmonary, Critical Care and Sleep Medicine, UC Davis Medical Center, Sacramento, CA (I.C.-P.).
Jeffrey WangDivision of Cardiology, Emory University School of Medicine, Atlanta, GA (J.W.).ORCID 0000-0002-6900-8268
Junfeng SunCritical Care Medicine Department, Clinical Center (V.J.F., J.S., R.L.D., P.Q.E., M.A.S., C.N.), National Institutes of Health, Bethesda, MD.
Tracy C ShieldsNIH Library, Office of Research Services, Office of the Director (T.C.S.), National Institutes of Health, Bethesda, MD.ORCID 0000-0001-5670-7388
Robert L DannerCritical Care Medicine Department, Clinical Center (V.J.F., J.S., R.L.D., P.Q.E., M.A.S., C.N.), National Institutes of Health, Bethesda, MD.ORCID 0000-0001-5715-3823
Peter Q EichackerCritical Care Medicine Department, Clinical Center (V.J.F., J.S., R.L.D., P.Q.E., M.A.S., C.N.), National Institutes of Health, Bethesda, MD.
Michael A SolomonCritical Care Medicine Department, Clinical Center (V.J.F., J.S., R.L.D., P.Q.E., M.A.S., C.N.), National Institutes of Health, Bethesda, MD.ORCID 0000-0001-7400-6614
Harvey G KleinDepartment of Transfusion Medicine, Clinical Center (H.G.K.), National Institutes of Health, Bethesda, MD.ORCID 0000-0002-4625-8467
Charles NatansonCritical Care Medicine Department, Clinical Center (V.J.F., J.S., R.L.D., P.Q.E., M.A.S., C.N.), National Institutes of Health, Bethesda, MD.ORCID 0000-0001-9712-2538

Funding

Preclinical and Clinical Investigations of Severe Infection and Critical Illness ZIACL008060 · CLC · CLINICAL CENTER · PI DANNER, ROBERT L · 2009 to 2025
$0k
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cardiovascular DiseasesErythrocyte TransfusionClinical Decision-MakingHemorrhageHumansRisk AssessmentRisk FactorsTreatment Outcomeanemiacardiac surgical procedureserythrocytesorthopedic proceduresuncertainty

Identifiers

PMID38747144
PMCPMC11186712

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.