ArticleJournal of periodontal research2024
Implant surface modifications and their impact on osseointegration and peri-implant diseases through epigenetic changes: A scoping review.
Article in Journal of periodontal research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Early Microbiological and Immunological Parameters in Sandblasted, Large-Grit Acid-Etched Implant Surfaces: A Split Mouth Randomized Clinical Trial.Clinical oral implants research · 2026Trial
- Convergent methodologies in prosthetic joint infection research: integrating transdisciplinary approaches to understand and prevent biofilm-driven failure of orthopaedic prostheses.Journal of medical microbiology · 2026Review
- Epigenetic Connections in Malocclusion.International journal of molecular sciences · 2026Review
- Machine Learning and Artificial Intelligence in Metallic Orthopedic Implant Development: A Narrative Review.Materials (Basel, Switzerland) · 2026Review
- Fatigue Behavior of Dental Implants Affected by Peri-Implantitis-Related Bone Loss: Influence of Implantoplasty Evaluated Through In Vitro Testing and Finite Element Modeling.Dentistry journal · 2026Article
- Mechanical Fatigue of Titanium Dental Implants After Implantoplasty: An In Vitro Study Combined with Finite Element Simulations.Journal of functional biomaterials · 2026Article
- Multiscale Interface Engineering for Orthopedic and Dental Implants: A Review.Journal of functional biomaterials · 2026Review
- Prevalence and Risk Indicators of Peri-Implant Diseases and Buccal Soft-Tissue Dehiscence: A Cross-Sectional Study From a University-Based Cohort.Journal of periodontal research · 2026Article
- Impact of Zirconia and Titanium Implant Surfaces of Different Roughness on Oral Epithelial Cells.Dentistry journal · 2026Article
- Beyond bioactivity: Chitosan macromolecular coatings on titanium surfaces drive osseointegration and immune suppression through targeted epigenetic regulation.Iranian journal of basic medical sciences · 2026Article
- Immunohistochemical evaluation of bone regeneration induced by human umbilical cord mesenchymal stem cells around implants in an osteoporotic rat model.Journal of dental sciences · 2026Article
- Dual Growth Factor Release From Collagen Based Multilayer Films on Ti-Surfaces Enhances Periimplant Bone Formation and Angiogenic Activity-An Experimental In-Vivo Study.Clinical oral implants research · 2026Article
- Mapping Immune-Inflammatory Niches on Zirconia Bone Implants: Single-Cell Transcriptomic Profiling.Research (Washington, D.C.) · 2026Article
- In Vitro Assessment of a Novel Piranha-Passivated Dental Implant Surface Against Oral Biofilm Formation.Clinical oral implants research · 2025Article
- Redefining Success in Implant Dentistry: Beyond Mere Implant Placement.Journal of periodontal research · 2025Article
- Preparation of high-quality pure titanium SLA surface and evaluation of its physicochemical and biological properties - in vitro experiments.BMC oral health · 2025Article
- Different Innovative Laser Implants Characteristics Histomorphometric and SEM-EDX Comparison for In Vivo Applications.Materials (Basel, Switzerland) · 2025Article
- The Novel iMPACT Tool and Quadrant Protocol for Peri-Implantitis: Surface Refinement and Re-Osseointegration Validated by SEM/EDS and Long-Term Clinical Case Reports.Medicina (Kaunas, Lithuania) · 2025Article
- Vitamin D3-Coated Surfaces and Their Role in Bone Repair and Peri-Implant Biomechanics.Biology · 2025Article
- Comparison Between Micro- and Micro-Nano Surface Texturization in the Initial Osseointegration Process: An Experimental In Vitro and In Vivo Preclinical Study.Bioengineering (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Dental implant surfaces and their unique properties can interact with the surrounding oral tissues through epigenetic cues. The present scoping review provides current perspectives on surface modifications of dental implants, their impact on the osseointegration process, and the interaction between implant surface properties and epigenetics, also in peri-implant diseases. Findings of this review demonstrate the impact of innovative surface treatments on the epigenetic mechanisms of cells, showing promising results in the early stages of osseointegration. Dental implant surfaces with properties of hydrophilicity, nanotexturization, multifunctional coatings, and incorporated drug-release systems have demonstrated favorable outcomes for early bone adhesion, increased antibacterial features, and improved osseointegration. The interaction between modified surface morphologies, different chemical surface energies, and/or release of molecules within the oral tissues has been shown to influence epigenetic mechanisms of the surrounding tissues caused by a physical-chemical interaction. Epigenetic changes around dental implants in the state of health and disease are different. In conclusion, emerging approaches in surface modifications for dental implants functionalized with epigenetics have great potential with a significant impact on modulating bone healing during osseointegration.
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Registered trials
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