Evidence map›Paper›PMID 38746961›Full record

ArticleLa Tunisie medicale2024

Ischemic Stroke in Young Tunisian Adults.

Dhaker Turki, Salma Sakka, Lamia Mbarek, Faten Triki, Mounir Ben Jemaa, Khadija Moalla, Sameh Marzouk, Olfa Turki, Fatma Megdiche, Choumous Kallel and 2 more

Abstract read
In one paragraph

Article in La Tunisie medicale, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dhaker TurkiLaboratory of neurogenetics, Parkinson's disease and cerebrovascular disease (LR-12-SP-19), Habib Bourguiba University Hospital, University of Sfax, Tunisia.
Salma SakkaLaboratory of neurogenetics, Parkinson's disease and cerebrovascular disease (LR-12-SP-19), Habib Bourguiba University Hospital, University of Sfax, Tunisia.
Lamia MbarekLaboratory of neurogenetics, Parkinson's disease and cerebrovascular disease (LR-12-SP-19), Habib Bourguiba University Hospital, University of Sfax, Tunisia.
Faten TrikiDepartment of cardiology, Hedi Cheker hospital, Sfax University, Sfax, Tunisia.
Mounir Ben JemaaDepartment of infectious diseases, Hedi Cheker hospital, Sfax university, Sfax, Tunisia.
Khadija MoallaLaboratory of neurogenetics, Parkinson's disease and cerebrovascular disease (LR-12-SP-19), Habib Bourguiba University Hospital, University of Sfax, Tunisia.
Sameh MarzoukHedi Chaker hospital, department of internal medicine, Sfax, Tunisia.
Olfa TurkiDepartment of intensive care, Habib Bourguiba University Hospital, University, Sfax, Tunisia.
Fatma MegdicheLaboratory of hematology, Hbib Bourguiba University Hospital Sfax, Tunisia.
Choumous KallelLaboratory of hematology, Hbib Bourguiba University Hospital Sfax, Tunisia.
Mariem DamakLaboratory of neurogenetics, Parkinson's disease and cerebrovascular disease (LR-12-SP-19), Habib Bourguiba University Hospital, University of Sfax, Tunisia.
Chokri MhiriLaboratory of neurogenetics, Parkinson's disease and cerebrovascular disease (LR-12-SP-19), Habib Bourguiba University Hospital, University of Sfax, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIschemic Stroke in young adults is a real public health problem; it's a major cause of disability, alters quality of life and has a great socio-economic impact.

aimdetermine risk factors and specify the etiology of arterial ischemic stroke in young Tunisian adults.

methodsIn this 5 years retrospective study (2015-2020), we included all young adults (18-50 years) admitted for arterial ischemic stroke (AIS). Risk factors were registered and analyzed. All patients were investigated using a standard protocol: biological tests, brain imaging, carotid ultrasound and cardiac assessment. Additional investigations were carried out at the discretion of the treating physician. The cause of ischemic stroke was classified according to the TOAST criteria.

resultsWe collected 200 patients with AIS. The mean age was 41.37 years ± 6.99. Traditional vascular risk factors were observed in more than 1⁄4 patients. A definite cause of stroke was identified in 120 patients. Cardio-embolic causes were the most common among our patients (19%) followed by atherosclerosis of the large arteries (11.5%). Other determined etiologies were found in 27.5% of patients. The etiology remained unclear in 40% of cases: undetermined despite complete investigation in 17.5%, undetermined and incompletely investigated 14.5 % and more than one potential pathomechanisms in 8%.

conclusionThrough this study, we demonstrated the diversity of etiology of stroke in young Tunisian adults. Changes of lifestyle are responsible for the occurrence of the traditional risk factors at an early age. Rheumatic heart diseases remain a frequent cause of AIS in our area.

Indexed as

Ischemic StrokeAdolescentAdultBrain IschemiaFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsTunisiaYoung AdultArterial ischemic strokeG20210A mutationrisk factors prothrombinstroke etiologyyoung adults

Identifiers

PMID38746961
PMCPMC11387991

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.