Evidence map›Paper›PMID 38746908›Full record

ReviewBreathe (Sheffield, England)2024

Imaging in the diagnosis and management of fibrosing interstitial lung diseases.

Christoph Lederer, Monika Storman, Adam Domonkos Tarnoki, David Laszlo Tarnoki, George A Margaritopoulos, Helmut Prosch

Registry-linked trialAbstract readReview
In one paragraph

Review in Breathe (Sheffield, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06844331 (ULtrasOund Applicability in the Assessment of Patients With fibRosing Interstitial Lung Disease), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06844331 enrolling by invitationnot on this map

ULtrasOund Applicability in the Assessment of Patients With fibRosing Interstitial Lung Disease (LORD): A Research Protocol of a Single Center, Real-life, Prospective Observational Study

TypeobservationalSponsorOdense University HospitalRan2024 to 2026Enrolled117ConditionsFibrosing Interstitial Lung Diseases, Thoracic UltrasoundArmsThoracic ultrasound
3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
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  5. Progressive pulmonary fibrosis.European radiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Christoph LedererCenter for Interstitial and Rare Lung Diseases, Pneumology, Thoraxklinik Heidelberg, University Hospital Heidelberg and German Center for Lung Research (DZL), Heidelberg, Germany.
Monika StormanDepartment of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, Warsaw, Poland.
Adam Domonkos TarnokiMedical Imaging Centre, Semmelweis University, Budapest, Hungary.
David Laszlo TarnokiMedical Imaging Centre, Semmelweis University, Budapest, Hungary.
George A MargaritopoulosILD Unit, "G. Papanikolaou" University Hospital, Thessaloniki, Greece.ORCID https://orcid.org/0000-0003-1418-8596
Helmut ProschDepartment of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0002-6119-6364

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-resolution computed tomography (HRCT) plays a pivotal role in the diagnosis and management of interstitial lung diseases (ILDs), particularly given the approval of antifibrotic agents for conditions like idiopathic pulmonary fibrosis and progressive pulmonary fibrosis. Diagnosing fibrotic pulmonary disorders through HRCT involves a detailed and methodical examination. The identification of specific lung tissue changes, including ground-glass opacities and reticulation, along with signs of fibrosis like honeycombing, traction bronchiectasis and lung volume loss, establishes clear HRCT patterns indicative of various ILDs. The reliability of these patterns in predicting pathological conditions depends largely on the clinical context. For instance, when a usual interstitial pneumonia pattern is present, the predictive value of this diagnosis is so high that a lung biopsy is considered to be redundant. This review intends to delineate the HRCT signs of fibrosis, elucidate the specific radiological patterns of fibrotic lung diseases, and identify the clinical circumstances under which these patterns emerge. Additionally, we introduce and discuss novel imaging techniques that hold promise for the diagnosis, screening and early detection of ILDs.

Identifiers

PMID38746908
PMCPMC11091715

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.