Evidence map›Paper›PMID 38746658›Full record

ArticleFrontiers in neurology2024

Combination of anodal tDCS of the cerebellum with a goal-oriented motor training to treat cervical dystonia: a pilot case series.

Jean-Pierre Bleton, Charlotte Cossé, Tiphanie Caloc'h, Alcira Suarez Moreno, Elisabeth Diverres, Pascal Derkinderen, Julien Nizard, Jean-Pascal Lefaucheur, Jean-Paul Nguyen

Abstract read
In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jean-Pierre BletonNeurology Department, Clinical Research Department, Hôpital Fondation Adolphe de Rothschild, Paris, France.
Charlotte CosséUnité de Stimulation Transcrânienne, Clinique Bretéché, Groupe Elsan, Nantes, France.
Tiphanie Caloc'hUnité de Stimulation Transcrânienne, Clinique Bretéché, Groupe Elsan, Nantes, France.
Alcira Suarez MorenoUnité de Stimulation Transcrânienne, Clinique Bretéché, Groupe Elsan, Nantes, France.
Elisabeth DiverresUnité de Stimulation Transcrânienne, Clinique Bretéché, Groupe Elsan, Nantes, France.
Pascal DerkinderenService de Neurologie, CHU de Nantes, Nantes, France.
Julien NizardService Douleur, Soins Palliatifs et de Support et UIC22, Hôpital Laennec, CHU, Nantes, France.
Jean-Pascal LefaucheurEA 4391, Équipe ENT (Nerve Excitability and Therapeutics), Université Paris-Est Créteil, Créteil, France.
Jean-Paul NguyenUnité de Stimulation Transcrânienne, Clinique Bretéché, Groupe Elsan, Nantes, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Transcranial Direct Current Stimulation (tDCS) of the cerebellum shows promise for the treatment of dystonia. Specific motor rehabilitation programs have also been developed in this context. However, the combination of these two approaches has not yet been evaluated to determine their therapeutic potential. Methods: We report a series of 5 patients with cervical dystonia (CD) poorly controlled by botulinum toxin injections. They were initially treated by a protocol of repeated daily sessions (for 3 or 5 days) of cerebellar anodal tDCS (cer-atDCS) applied alone. In a second time, additional protocols of cer-atDCS were performed in combination with a program of goal-oriented motor training exercises (Mot-Training), specifically developed for the treatment of CD. The clinical impact of the procedures was assessed on the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS). Results: Compared to baseline, the maximum percentage of TWSTRS total score improvement was 37% on average after cer-atDCS performed alone ( Conclusion: The combination of cer-atDCS with Mot-Training produced a greater and more prolonged improvement than the application of cer-atDCS alone. Such a combined therapeutic procedure is easy to perform and opens important perspectives in the long-term treatment of CD. These results remain to be confirmed by a randomized sham-controlled trial on a larger sample.

Indexed as

cerebellar stimulationcervical dystoniamotor trainingneuromodulationnon-invasive brain stimulationrehabilitationtranscranial direct current stimulation

Identifiers

PMID38746658
PMCPMC11091337

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.