ArticlebioRxiv : the preprint server for biology2024
Reduced Levels of Lagging Strand Polymerases Shape Stem Cell Chromatin.
Jonathan Snedeker, Brendon E M Davis, Rajesh Ranjan, Matthew Wooten, Joshua Blundon, Xin Chen
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
6 authors.
Jonathan SnedekerDepartment of Biology, The Johns Hopkins University, Baltimore, MD 21218, USA.
Brendon E M DavisDepartment of Biology, The Johns Hopkins University, Baltimore, MD 21218, USA.
Rajesh RanjanDepartment of Biology, The Johns Hopkins University, Baltimore, MD 21218, USA.
Joshua BlundonDepartment of Biology, The Johns Hopkins University, Baltimore, MD 21218, USA.
Funding
CELLULAR AND MOLECULAR BIOLOGYT32GM007231 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI VAN DOREN, MARK B · 1985 to 2020
$18.4MCellular and Molecular BiologyT32GM141804 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI John Kim · 2021 to 2026
$5.1MStudy epigenetic inheritance during development, homeostasis and regenerationR35GM127075 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Xin Chen · 2018 to 2026
$3.2MEpigenetic Regulation of Germ Cell Differentiation from a Stem Cell LineageR01HD102474 · NICHD · JOHNS HOPKINS UNIVERSITY · PI CHEN, XIN · 2020 to 2024
$1.7MInvestigating the mechanisms and generality of asymmetric histone inheritance in multiple stem cell systemsF31GM115149 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI WOOTEN, MATTHEW · 2016 to 2017
$88kInvestigating the molecular mechanisms of asymmetric histone incorporation during DNA replicationF31HD104526 · NICHD · JOHNS HOPKINS UNIVERSITY · PI SNEDEKER, JONATHAN · 2021 to 2022
$66kNICHD NIH HHS F31 HD104526NICHD NIH HHS R01 HD102474NIGMS NIH HHS F31 GM115149NIGMS NIH HHS R35 GM127075NIGMS NIH HHS T32 GM007231NIGMS NIH HHS T32 GM141804
6 · The paper itselfAbstract
Stem cells display asymmetric histone inheritance while non-stem progenitor cells exhibit symmetric patterns in the
Indexed as
asymmetric cell divisioncellular differentiationchromatin fiberDNA fiberDNA replicationgermline stem celllagging strand synthesisreplication-dependent histone incorporation
Identifiers
PMID38746451
PMCPMC11092439
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