Evidence map›Paper›PMID 38746388›Full record

ArticlebioRxiv : the preprint server for biology2024

Tau filaments with the Alzheimer fold in cases with

Chao Qi, Sofia Lövestam, Alexey G Murzin, Sew Peak-Chew, Catarina Franco, Marika Bogdani, Caitlin Latimer, Jill R Murrell, Patrick W Cullinane, Zane Jaunmuktane and 4 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Chao QiMRC Laboratory of Molecular Biology, Cambridge, UK.ORCID 0000-0003-1277-0363
Sofia LövestamMRC Laboratory of Molecular Biology, Cambridge, UK.ORCID 0000-0002-2152-1476
Alexey G MurzinMRC Laboratory of Molecular Biology, Cambridge, UK.
Sew Peak-ChewMRC Laboratory of Molecular Biology, Cambridge, UK.
Catarina FrancoMRC Laboratory of Molecular Biology, Cambridge, UK.
Marika BogdaniDepartments of Neurology and Pathology, University of Washington, Seattle, USA.
Caitlin LatimerDepartments of Neurology and Pathology, University of Washington, Seattle, USA.
Jill R MurrellDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, USA.
Patrick W CullinaneDepartment of Clinical and Movement Neurosciences, Queen Square Institute of Neurology, University College, London UK.
Zane JaunmuktaneDepartment of Clinical and Movement Neurosciences, Queen Square Institute of Neurology, University College, London UK.
Thomas D BirdDepartments of Neurology and Pathology, University of Washington, Seattle, USA.
Bernardino GhettiDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, USA.
Sjors H W ScheresMRC Laboratory of Molecular Biology, Cambridge, UK.ORCID 0000-0002-0462-6540
Michel GoedertMRC Laboratory of Molecular Biology, Cambridge, UK.ORCID 0000-0002-5214-7886

Funding

Research Education ComponentP30AG010133 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI SAYKIN, ANDREW J · 1991 to 2020
$37.3M
Research Education ComponentP30AG072976 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI ANDREW J SAYKIN · 2021 to 2026
$24.1M
Identification of novel four repeat tauopathies through analysis of network vulnerability, tau structure and propagation.R01AG080001 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI BERNARDINO Francesco GHETTI, RUBEN VIDAL · 2023 to 2026
$2.7M
Structural analysis of tau associated with parenchymal and vascular prion protein amyloidosisRF1AG071177 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI GHETTI, BERNARDINO FRANCESCO, JIANG, WEN · 2021 to 2021
$2.3M
NIA NIH HHS P30 AG010133NIA NIH HHS P30 AG072976NIA NIH HHS R01 AG080001NIA NIH HHS RF1 AG071177
6 · The paper itself

Abstract

Frontotemporal dementia (FTD) and Alzheimer's disease are the most common forms of early-onset dementia. Dominantly inherited mutations in

Identifiers

PMID38746388
PMCPMC11092478

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.