Evidence map›Paper›PMID 38746290›Full record

ArticleResearch square2024

Long COVID incidence in adults and children between 2020 and 2023: a real-world data study from the RECOVER Initiative.

Hannah Mandel, Yun Yoo, Andrea Allen, Sajjad Abedian, Zoe Verzani, Elizabeth Karlson, Lawrence Kleinman, Praveen Mudumbi, Carlos Oliveira, Jennifer Muszynski and 33 more

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In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

43 authors.

Hannah MandelNew York University Grossman School of Medicine.
Yun YooEmory University.
Andrea AllenChildren's Hospital of Philadelphia.ORCID 0000-0001-9846-0280
Sajjad AbedianWeill Cornell Medicine.
Zoe VerzaniWeill Cornell Medical College.ORCID 0000-0001-6183-9254
Elizabeth KarlsonBrigham and Women's Hospital.
Lawrence KleinmanRutgers Robert Wood Johnson Medical School.ORCID 0000-0002-4024-2229
Praveen MudumbiNew York University Grossman School of Medicine.ORCID 0000-0003-3792-1789
Carlos OliveiraYale University.ORCID 0000-0003-1897-6581
Jennifer MuszynskiNationwide Children's Hospital.
Rachel GrossNew York University Grossman School of Medicine.
Thomas CartonLouisiana Public Health Institute.
C KimRECOVER Patient, Caregiver, or Community Advocate Representative.ORCID 0000-0002-3881-1592
Emily TaylorRECOVER Patient, Caregiver, or Community Advocate Representative.
Heekyong ParkMass General Brigham.ORCID 0000-0001-9481-3288
Jasmin DiversNew York University, USA.
J KellyUniversity of California, San Francisco.ORCID 0000-0002-7616-0321
Jonathan ArnoldUniversity of Pittsburgh School of Medicine.
Carol GearyUniversity of Nebraska Medical Center.
Chengxi ZangWeill Cornell Medicine.ORCID 0000-0002-8244-9551
Kelan TantisiraDivision of Respiratory Medicine, Department of Pediatrics, University of California San Diego, San Diego.
Kyung RheeUniversity of California, San Diego.
Michael KoropsakWeill Cornell Medical College.
Sindhu MohandasChildren's Hospital Los Angeles/University of Southern California.ORCID 0000-0002-8397-6249
Andrew VaseyUniversity of Nebraska Medical Center.ORCID 0000-0003-3084-7416
Mark WeinerWeill Cornell Medicine.ORCID 0000-0001-5586-9940
Abu MosaUniversity of Missouri School of Medicine.
Melissa HaendelUniversity of Colorado Anschutz Medical Campus.
Christopher ChuteJohns Hopkins University.ORCID 0000-0001-5437-2545
Shawn MurphyMassachusetts General Hospital.ORCID 0000-0002-1905-8806
Lisa O'BrienRECOVER Patient, Caregiver, or Community Advocate Representative.
Jacqueline SzmuszkoviczChildrens Hospital Los Angeles.ORCID 0000-0001-5626-2083
Nicholas GütheRECOVER Patient, Caregiver, or Community Advocate Representative.
Jorge SantanaUniversity of Puerto Rico.
Aliva DeColumbia University Irving Medical Center.ORCID 0000-0001-6995-5823
Amanda BogieUniversity of Oklahoma Health Sciences Center.ORCID 0000-0003-0642-9310
Katia HalabiNationwide Children's Hospital.
Lathika MohanrajVirginia Commonwealth University School of Nursing.
Patricia KinserVirginia Commonwealth University School of Nursing.
Samuel PackardColumbia University Mailman School of Public Health.ORCID 0000-0001-8607-792X
Katherine TuttleUniversity of Washington.ORCID 0000-0002-2235-0103
Lorna ThorpeNew York University Grossman School of Medicine.
Richard MoffittEmory University.ORCID 0000-0003-2723-5902

Funding

OTA-21-015A Post-Acute Sequelae of SARS-CoV-2 Infection Initiative: NYU Langone Health Clinical Science Core, Data Resource Core, and PASC Biorepository CoreOT2HL161847 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GROSS, RACHEL SHARON, HORWITZ, LEORA · 2021 to 2025
$651.0M
Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
Clinical and Translational Science InstituteUL1TR001872 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COLLARD, HAROLD R, JACOBY, VANESSA · 2016 to 2025
$112.1M
Project-005UL1TR001445 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BREDELLA, MIRIAM ANTOINETTE, HOCHMAN, JUDITH S · 2015 to 2025
$103.5M
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4M
Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
The Harvard Clinical and Translational Science CenterUL1TR002541 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2018 to 2022
$93.0M
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6 · The paper itself

Abstract

Estimates of post-acute sequelae of SARS-CoV-2 infection (PASC) incidence, also known as Long COVID, have varied across studies and changed over time. We estimated PASC incidence among adult and pediatric populations in three nationwide research networks of electronic health records (EHR) participating in the RECOVER Initiative using different classification algorithms (computable phenotypes). Overall, 7% of children and 8.5%-26.4% of adults developed PASC, depending on computable phenotype used. Excess incidence among SARS-CoV-2 patients was 4% in children and ranged from 4-7% among adults, representing a lower-bound incidence estimation based on two control groups - contemporary COVID-19 negative and historical patients (2019). Temporal patterns were consistent across networks, with peaks associated with introduction of new viral variants. Our findings indicate that preventing and mitigating Long COVID remains a public health priority. Examining temporal patterns and risk factors of PASC incidence informs our understanding of etiology and can improve prevention and management.

Identifiers

PMID38746290
PMCPMC11092818

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.