Evidence map›Paper›PMID 38746226›Full record

ArticleResearch square2024

Innate biosignature of treatment failure in human cutaneous leishmaniasis.

Maria Adelaida Gómez, Ashton Trey Belew, Deninson Vargas, Lina Giraldo-Parra, David Rebellón-Sanchez, Theresa Alexander, Najib El Sayed

Abstract readPreprint
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Maria Adelaida GómezCentro Internacional de Entrenamiento e Investigaciones Médicas.ORCID 0000-0001-8792-1563
Ashton Trey BelewUniversity of Maryland.
Deninson VargasCentro Internacional de Entrenamiento e Investigaciones Médicas.
Lina Giraldo-ParraCentro Internacional de Entrenamiento e Investigaciones Médicas - CIDEIM.ORCID 0000-0002-3558-7249
David Rebellón-SanchezCentro Internacional de Entrenamiento e Investigaciones Médicas.
Theresa AlexanderUniversity of Maryland.
Najib El SayedUniversity of Maryland.ORCID 0000-0001-7970-3312

Funding

Vector/Host-Parasite Interface of Leishmaniasis in ColombiaD43TW006589 · FIC · YALE UNIVERSITY · PI GORE SARAVIA, NANCY, TSCHUDI, CHRISTIAN · 2003 to 2024
$4.3M
The Innate Immune Response As A Therapeutic Target For Cutaneous LeishmaniasisU19AI129910 · NIAID · CENTRO INTERNACIONAL (CIDEIM) · PI GORE SARAVIA, NANCY · 2017 to 2021
$2.8M
Host and parasite determinants of Leishmania Viannia persistence in naturally infected human populationsR01AI172887 · NIAID · UNIV OF MARYLAND, COLLEGE PARK · PI Najib M El-Sayed, Maria Adelaida Gomez · 2023 to 2026
$2.4M
FIC NIH HHS D43 TW006589NIAID NIH HHS R01 AI172887NIAID NIH HHS U19 AI129910Wellcome Trust
6 · The paper itself

Abstract

The quality and magnitude of the immune and inflammatory responses determine the clinical outcome of

Indexed as

antimonyCutaneous leishmaniasisinnate immunityRNA-Seqtreatment failure

Identifiers

PMID38746226
PMCPMC11092798

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.