Evidence map›Paper›PMID 38746046›Full record

ArticleJournal of fluid mechanics2024

An analytic model for the flow induced in syringomyelia cavities.

G L Nozaleda, J Alaminos-Quesada, W Coenen, V Haughton, A L Sánchez

Abstract read
In one paragraph

Article in Journal of fluid mechanics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

G L NozaledaDepartment of Mechanical and Aerospace Engineering, University of California San Diego, La Jolla, CA 92093-0411, USA.
J Alaminos-QuesadaDepartment of Mechanical and Aerospace Engineering, University of California San Diego, La Jolla, CA 92093-0411, USA.
W CoenenGrupo de Mecánica de Fluidos, Universidad Carlos III de Madrid, Leganés, 28911 Spain.
V HaughtonSchool of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, 53706 USA.
A L SánchezDepartment of Mechanical and Aerospace Engineering, University of California San Diego, La Jolla, CA 92093-0411, USA.

Funding

Development of Patient-Specific Mathematical Models for the Transport of Solute Molecules in the Cerebrospinal Fluid (CSF) Along the Spinal CanalR01NS120343 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SANCHEZ, ANTONIO LUIS · 2020 to 2024
$2.3M
NINDS NIH HHS R01 NS120343
6 · The paper itself

Abstract

A simple two-dimensional fluid-structure-interaction problem, involving viscous oscillatory flow in a channel separated by an elastic membrane from a fluid-filled slender cavity, is analyzed to shed light on the flow dynamics pertaining to syringomyelia, a neurological disorder characterized by the appearance of a large tubular cavity (syrinx) within the spinal cord. The focus is on configurations in which the velocity induced in the cavity, representing the syrinx, is comparable to that found in the channel, representing the subarachnoid space surrounding the spinal cord, both flows being coupled through a linear elastic equation describing the membrane deformation. An asymptotic analysis for small stroke lengths leads to closed-form expressions for the leading-order oscillatory flow, and also for the stationary flow associated with the first-order corrections, the latter involving a steady distribution of transmembrane pressure. The magnitude of the induced flow is found to depend strongly on the frequency, with the result that for channel flow rates of non-sinusoidal waveform, as those found in the spinal canal, higher harmonics can dominate the sloshing motion in the cavity, in agreement with previous

Identifiers

PMID38746046
PMCPMC11089288

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.