Evidence map›Paper›PMID 38745762›Full record

ArticleInnovation (Cambridge (Mass.))2024

A causal multiomics study discriminates the early immune features of Ad5-vectored Ebola vaccine recipients.

Zhe Zhang, Wenjing Yang, Zhengshan Chen, Haoang Chi, Shipo Wu, Wanru Zheng, Ruochun Jin, Busen Wang, Yudong Wang, Nan Huo and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Innovation (Cambridge (Mass.)), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Zhe ZhangInstitute of Biotechnology, Academy of Military Medical Sciences, Beijing 100071, China.
Wenjing YangDepartment of Intelligent Data Science, College of Computer Science and Technology, National University of Defense Technology, Changsha 410073, China.
Zhengshan ChenInstitute of Biotechnology, Academy of Military Medical Sciences, Beijing 100071, China.
Haoang ChiIntelligent Game and Decision Lab, Academy of Military Science, Beijing 100091, China.
Shipo WuInstitute of Biotechnology, Academy of Military Medical Sciences, Beijing 100071, China.
Wanru ZhengInstitute of Biotechnology, Academy of Military Medical Sciences, Beijing 100071, China.
Ruochun JinDepartment of Intelligent Data Science, College of Computer Science and Technology, National University of Defense Technology, Changsha 410073, China.
Busen WangInstitute of Biotechnology, Academy of Military Medical Sciences, Beijing 100071, China.
Yudong WangInstitute of Biotechnology, Academy of Military Medical Sciences, Beijing 100071, China.
Nan HuoInstitute of Biotechnology, Academy of Military Medical Sciences, Beijing 100071, China.
Jinlong ZhangInstitute of Biotechnology, Academy of Military Medical Sciences, Beijing 100071, China.
Xiaohong SongInstitute of Biotechnology, Academy of Military Medical Sciences, Beijing 100071, China.
Liyang XuDepartment of Intelligent Data Science, College of Computer Science and Technology, National University of Defense Technology, Changsha 410073, China.
Jun ZhangInstitute of Biotechnology, Academy of Military Medical Sciences, Beijing 100071, China.
Lihua HouInstitute of Biotechnology, Academy of Military Medical Sciences, Beijing 100071, China.
Wei ChenInstitute of Biotechnology, Academy of Military Medical Sciences, Beijing 100071, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The vaccine-induced innate immune response is essential for the generation of an antibody response. To date, how Ad5-vectored vaccines are influenced by preexisting anti-Ad5 antibodies during activation of the early immune response remains unclear. Here, we investigated the specific alterations in GP

Identifiers

PMID38745762
PMCPMC11092886

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.