Evidence map›Paper›PMID 38745468›Full record

ArticleVirulence2024

M1-type polarized macrophage contributes to brain damage through CXCR3.2/CXCL11 pathways after RGNNV infection in grouper.

Kaishan Liang, Minlin Zhang, Jiantao Liang, Xiaoling Zuo, Xianze Jia, Jinhong Shan, Zongyang Li, Jie Yu, Zijie Xuan, Liyuan Luo and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Virulence, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Kaishan LiangCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.
Minlin ZhangCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.
Jiantao LiangCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.
Xiaoling ZuoCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.
Xianze JiaCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.
Jinhong ShanCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.
Zongyang LiCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.
Jie YuCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.
Zijie XuanCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.
Liyuan LuoCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.
Huihong ZhaoCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.
Songyong GanGuangdong Marine Fishery Experiment Center, Agro-tech Extension Center of Guangdong Province, Huizhou, China.
Ding LiuGuangdong Havwii Agricultural Group Co. Ltd, Zhanjiang, China.
Qiwei QinCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.
Qing WangCollege of Marine Sciences, South China Agricultural University, Guangzhou, China.ORCID 0000-0001-5715-2062

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The vertebrate central nervous system (CNS) is the most complex system of the body. The CNS, especially the brain, is generally regarded as immune-privileged. However, the specialized immune strategies in the brain and how immune cells, specifically macrophages in the brain, respond to virus invasion remain poorly understood. Therefore, this study aimed to examine the potential immune response of macrophages in the brain of orange-spotted groupers (

Indexed as

BrainFish DiseasesMacrophagesNodaviridaeRNA Virus InfectionsAnimalsBassChemokine CXCL11CytokinesFish ProteinsReceptors, CXCR3Signal TransductionChemokine CXCL11CytokinesFish ProteinsReceptors, CXCR3Central nervous systemCXCR3.2macrophageproinflammatoryRGNNV

Identifiers

PMID38745468
PMCPMC11123556

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.