Evidence map›Paper›PMID 38745274›Full record

ArticleBMC oral health2024

Long-term haplodeficency of DSPP causes temporomandibular joint osteoarthritis in mice.

Qilin Liu, Yitong Zhao, Haibo Shi, Danwei Xiang, Chunye Wu, Lina Song, Ning Ma, Hongchen Sun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qilin LiuDepartment of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Jilin University, Changchun, China.
Yitong ZhaoDepartment of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Jilin University, Changchun, China.
Haibo ShiDepartment of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Jilin University, Changchun, China.
Danwei XiangDepartment of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Jilin University, Changchun, China.
Chunye WuDepartment of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Jilin University, Changchun, China.
Lina SongDepartment of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Jilin University, Changchun, China.
Ning MaDepartment of Rheumatology, The First Hospital, Jilin University, Changchun, China. mning@jlu.edu.cn.
Hongchen SunDepartment of Oral Pathology, School and Hospital of Stomatology, Jilin University, Changchun, China. hcsun@jlu.edu.cn.

Funding

Department of Finance of Jilin Province 2018SCZWSZX-034Department of Finance of Jilin Province JCSZ201978-10Department of Science and Technology of Jilin Province 20210101308JCDepartment of Science and Technology of Jilin Province YDZJ202201ZYTS050Jilin Provincial Department of Health 2015Q014Jilin University 2015340National Natural Science Foundation of China 81600890The Development and Reform Commission of Jilin Province 2016c044-3The Education Department of Jilin province [2016]-484
6 · The paper itself

Abstract

backgroundExtracellular matrix (ECM) protein malfunction or defect may lead to temporomandibular joint osteoarthritis (TMJ OA). Dentin sialophophoprotein (DSPP) is a mandibular condylar cartilage ECM protein, and its deletion impacted cell proliferation and other extracellular matrix alterations of postnatal condylar cartilage. However, it remains unclear if long-term loss of function of DSPP leads to TMJ OA. The study aimed to test the hypothesis that long-term haploinsufficiency of DSPP causes TMJ OA. MATERIALS AND

methodsTo determine whether Dspp

resultsMicro-CT and histomorphometric analyses revealed that Dspp

conclusionsDspp

Indexed as

Extracellular Matrix ProteinsOsteoarthritisPhosphoproteinsSialoglycoproteinsTemporomandibular Joint DisordersAnimalsDentin SialophosphoproteinMandibular CondyleMiceTemporomandibular JointX-Ray MicrotomographyDentin SialophosphoproteinExtracellular Matrix ProteinsPhosphoproteinsSialoglycoproteinsDentin sialophosphoproteinKnockout miceMandibular condylar cartilageOsteoarthritisSubchondral boneTemporomandibular joint

Identifiers

PMID38745274
PMCPMC11094853

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.